Selective modulation of interhemispheric connectivity by transcranial alternating current stimulation influences binaural integration
Résumé
Significance Sensory processing depends upon the integration of widely distributed neural assemblies. During every day listening, our ears receive different information (due to interaural time and amplitude differences) and it is known that both hemispheres extract different acoustic features. Nonetheless, acoustic features belonging to the same source become integrated. It has been suggested that the brain overcomes this “binding problem” by synchronization of oscillatory activity across the relevant regions. Here we probe interhemispheric oscillatory synchronization as a mechanism for acoustic feature binding using bihemispheric transcranial alternating current stimulation. Concurrent functional MRI reveals that antiphase stimulation of auditory areas changes effective connectivity between these areas, and that this change in connectivity predicts perceptual integration of dichotic stimuli.
Domaines
Neurosciences
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presig_publication.pdf (1.57 Mo)
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kosem2014_Neuroimage.pdf (2.01 Mo)
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