A novel role for myeloid endothelin-B receptors in hypertension
Résumé
Hypertension is common. Recent data suggest that macrophages (M/) contribute to, and protect from, hypertension. Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor with additional pro-inflammatory properties. We investigated the role of the ET system in experimental and clinical hypertension by modifying M/ number and phenotype.
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