Kimberle Crenshaw was the first to identify the challenges of intersectional claims in law. On the European level, the term most often used is multiple discrimination. After 50 years of implementation of civil rights legislation, the United States offers a unique critique of the scope and the limits of anti-discrimination law. The interpretation of concepts like disparate treatment and disparate impact discrimination in employment reveals the complexity of individual and systemic discrimination. American empirical studies of the grounds of discrimination reflect issues of equality and liberty. The transatlantic comparison allows us to revisit the analysis of the intersections between forms or systems of oppression, domination, or discrimination in law from a different standpoint in Europe.