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Article Dans Une Revue Processes Année : 2022

Special Issue on “Frontiers in Connecting Steady-State and Dynamic Approaches for Modelling Cell Metabolic Behavior”

Résumé

Understanding the behaviour of cell metabolism is the crucial key in bioprocess development and optimization, as well as in the development of efficient therapies. Indeed, it is established that a cell’s behaviour relies on its genetics, and more practically on gene expression, and thus on metabolic pathways’ activity. There are currently two fundamental trends in the analysis of metabolic networks: the constraint-based modelling (CBM) approach for large-size networks, which is used to determine a space for a feasible metabolic steady-state flux solution, and the kinetic metabolic modelling approach for relatively small-size networks, which is used to study the dynamic behaviour of a regulated metabolic system.
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hal-03903344 , version 1 (15-07-2024)

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Sabine Peres, Mario Jolicoeur. Special Issue on “Frontiers in Connecting Steady-State and Dynamic Approaches for Modelling Cell Metabolic Behavior”: Editorial. Processes, 2022, Frontiers in Connecting Steady-State and Dynamic Approaches for Modelling Cell Metabolic Behavior), 10 (8), pp.1612. ⟨10.3390/pr10081612⟩. ⟨hal-03903344⟩
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