Kinetic and Dynamic Kinetic Resolution by Dual Catalysis - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue European Journal of Organic Chemistry Année : 2022

Kinetic and Dynamic Kinetic Resolution by Dual Catalysis

Résumé

Kinetic resolution is one of the most common methods to access enantiomerically enriched compounds. In this method, the resolution is based on the existing difference in reaction rates of the two enantiomers with a chiral catalyst. In the dynamic kinetic resolution, the less reactive enantiomer is racemized and the racemic mixture is further resolved, leading eventually to complete transformation to an enantioenriched compound. This review summarizes the dual catalytic strategies (i. e., modular combinations of distinct catalysts) that have been applied to kinetic resolution and dynamic kinetic resolution. We focus upon the role of the two catalysts, the compatibility between them, and the practical benefits.
Fichier non déposé

Dates et versions

hal-03888810 , version 1 (07-12-2022)

Identifiants

Citer

Gangavara Thejashree, Eric Doris, Edmond Gravel, Irishi Namboothiri. Kinetic and Dynamic Kinetic Resolution by Dual Catalysis. European Journal of Organic Chemistry, 2022, 2022 (44), ⟨10.1002/ejoc.202201035⟩. ⟨hal-03888810⟩
17 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More