Context-dependent selectivity to natural images in the retina - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Nature Communications Année : 2022

Context-dependent selectivity to natural images in the retina

Résumé

Retina ganglion cells extract specific features from natural scenes and send this information to the brain. In particular, they respond to local light increase (ON responses), and/or decrease (OFF). However, it is unclear if this ON-OFF selectivity, characterized with synthetic stimuli, is maintained under natural scene stimulation. Here we recorded ganglion cell responses to natural images slightly perturbed by random noise patterns to determine their selectivity during natural stimulation. The ON-OFF selectivity strongly depended on the specific image. A single ganglion cell can signal luminance increase for one image, and luminance decrease for another. Modeling and experiments showed that this resulted from the non-linear combination of different retinal pathways. Despite the versatility of the ON-OFF selectivity, a systematic analysis demonstrated that contrast was reliably encoded in these responses. Our perturbative approach uncovered the selectivity of retinal ganglion cells to more complex features than initially thought.
Fichier principal
Vignette du fichier
s41467-022-33242-8.pdf (1.94 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Licence : CC BY - Paternité

Dates et versions

hal-03854587 , version 1 (15-11-2022)

Licence

Paternité

Identifiants

Citer

Matías Goldin, Baptiste Lefebvre, Samuele Virgili, Mathieu Kim Pham van Cang, Alexander Ecker, et al.. Context-dependent selectivity to natural images in the retina. Nature Communications, 2022, 13 (1), pp.5556. ⟨10.1038/s41467-022-33242-8⟩. ⟨hal-03854587⟩
35 Consultations
14 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More