The Perkin Strategy for the Synthesis of Large Carboxy-Substituted Polycyclic Aromatic Compounds - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue European Journal of Organic Chemistry Année : 2022

The Perkin Strategy for the Synthesis of Large Carboxy-Substituted Polycyclic Aromatic Compounds

Résumé

An efficient and versatile synthetic approach has been developed for the synthesis of large carboxy-substituted polycyclic arenes. This strategy relies on Perkin reactions between arylacetic and arylglyoxylic acids for the formation of flexible precursors. A subsequent rigidification step, by catalyst-or light-induced intramolecular cyclization reactions, then yealds fully condensed polycyclic aromatic compounds. Protection and deprotection techniques have been developed to allow the controlled assembly of a large number of building blocks. This method can now be applied to the formation of planar or non-planar, linear or macrocyclic species of various sizes.
Fichier principal
Vignette du fichier
M3-Durola-Minireview Perkin.pdf (1.46 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03845635 , version 1 (10-11-2022)

Identifiants

Citer

Ludmilla Sturm, Frédéric Aribot, Luc Soliman, Harald Bock, Fabien Durola. The Perkin Strategy for the Synthesis of Large Carboxy-Substituted Polycyclic Aromatic Compounds. European Journal of Organic Chemistry, 2022, 2022 (29), pp.e202200196. ⟨10.1002/ejoc.202200196⟩. ⟨hal-03845635⟩

Collections

CNRS INC-CNRS ANR
26 Consultations
48 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More