A multi-step continuous flow synthesis of pomalidomide
Résumé
The immunomodulatory drugs (IMiDs) thalidomide, pomalidomide, and lenalidomide are widely used to treat multiple myeloma. The permanent need of IMiDs analogues in clinical screening and practice has created the demand to find a reliable and robust method for their preparation. To reach this goal, the use of flow chemistry is quite appealing, allowing a safe operation, an excellent reproducibility and an efficient process.
Domaines
Chimie| Origine | Fichiers produits par l'(les) auteur(s) |
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