Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis
Résumé
Modulating cytosine hydroxymethylation by inhibiting TET1 activity prevents osteoarthritis in mice.
Article Dans Une Revue
Science Translational Medicine
Année : 2020
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https://hal.science/hal-03815589
Soumis le : vendredi 14 octobre 2022-17:07:29
Dernière modification le : samedi 7 octobre 2023-21:36:25
Citer
Piera Smeriglio, Fiorella Grandi, Spoorthi Davala, Venkata Masarapu, Pier Francesco Indelli, et al.. Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis. Science Translational Medicine, 2020, 12 (539), ⟨10.1126/scitranslmed.aax2332⟩. ⟨hal-03815589⟩
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