Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury

Development of novel nanomedicines to inhibit pro-inflammatory cytokine expression and reactive oxygen species (ROS) generation for anti-inflammatory therapy of acute lung injury (ALI) remains challenging. Here, we present a new nanomedicine platform based on tyramine-bearing two dimethylphosphonate sodium salt (TBP)-modified amphiphilic phosphorus dendron (C11G3) nanomicelles encapsulated with antioxidant drug curcumin (Cur).

Keywords

Phosphorus dendrons Nanomicelles Curcumin Alveolar macrophages NF-κB Acute lung injury

Domains

Biochemistry, Molecular Biology

Fichier principal

Li, Phosphorus dendron nanomicelles, 2022.pdf (2.95 Mo)

Origin	Publisher files allowed on an open archive

Marie-Hélène Gulli : Connect in order to contact the contributor

https://hal.science/hal-03807996

Submitted on : Monday, October 10, 2022-11:53:01 AM

Last modification on : Thursday, July 18, 2024-10:51:28 AM

Long-term archiving on : Wednesday, January 11, 2023-6:56:04 PM

Dates and versions

hal-03807996 , version 1 (10-10-2022)

Licence

Attribution

Identifiers

HAL Id : hal-03807996 , version 1
DOI : 10.7150/thno.70701

Cite

Jin Li, Liang Chen, Changsheng Li, Yu Fan, Mengsi Zhan, et al.. Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury. Theranostics, 2022, 12 (7), pp.3407-3419. ⟨10.7150/thno.70701⟩. ⟨hal-03807996⟩

Export

BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite

Collections

IRD CNRS LCC INC-CNRS UP-SCIENCES TOULOUSE-INP UNIV-UT3 UT3-TOULOUSEINP

99 View

38 Download