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Article Dans Une Revue Environmental Chemistry Letters Année : 2022

Green methodologies for the synthesis of 2-aminothiophene

Résumé

Pollution and the rising energy demand have prompted the design of new synthetic reactions that meet the principles of green chemistry. In particular, alternative synthesis of 2aminothiophene have recently focused interest because 2-aminothiophene is a unique 5membered S-heterocycle and a pharmacophore providing antiprotozoal, antiproliferative, antiviral, antibacterial or antifungal properties. Here, we review new synthetic routes to 2aminothiophenes, including multicomponent reactions, homogeneously-or heterogeneouslycatalyzed reactions, with focus on green pathways.
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Dates et versions

hal-03798752 , version 1 (05-10-2022)

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Valentin Duvauchelle, Patrick Meffre, Zohra Benfodda. Green methodologies for the synthesis of 2-aminothiophene. Environmental Chemistry Letters, 2022, ⟨10.1007/s10311-022-01482-1⟩. ⟨hal-03798752⟩

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