Article Dans Une Revue Archives of Microbiology Année : 2021

What do we know about osmoadaptation of Yersinia pestis?

Résumé

The plague agent Yersinia pestis mainly spreads among mammalian hosts and their associated fleas. Production of a successful mammal–flea–mammal life cycle implies that Y. pestis senses and responds to distinct cues in both host and vector. Among these cues, osmolarity is a fundamental parameter. The plague bacillus lives in a tightly regulated environment in the mammalian host, while osmolarity fluctuates in the flea gut (300–550 mOsM). Here, we review the mechanisms that enable Y. pestis to perceive fluctuations in osmolarity, as well as genomic plasticity and physiological adaptation of the bacterium to this stress.

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Dates et versions

hal-03795431 , version 1 (04-10-2022)

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Sébastien Bontemps-Gallo, Jean-Marie Lacroix, Florent Sebbane. What do we know about osmoadaptation of Yersinia pestis?. Archives of Microbiology, 2021, 204 (1), pp.11. ⟨10.1007/s00203-021-02610-1⟩. ⟨hal-03795431⟩
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