Article Dans Une Revue Journal of Open Source Software Année : 2021

Tyssue: an epithelium simulation library

Résumé

The tyssue Python library seeks to provide a unified interface to implement bio-mechanical models of living tissues. Its main focus is on vertex based epithelium models. tyssue allows to model the mechanical behavior of 2D, apical 3D or full 3D epithelia based on the numerical resolution of the equations of motion for the mesh vertices. Biological processes are modeled through changes in the topological and dynamical properties of the mesh. tyssue is a modular library. Starting with the same tissue geometry, the choice of constraints, energy potential terms and parameters increases the possibility to answer different biological questions and easily explore mechanical hypotheses.

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hal-03765428 , version 1 (31-08-2022)

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Sophie Theis, Magali Suzanne, Guillaume Gay. Tyssue: an epithelium simulation library. Journal of Open Source Software, 2021, 6 (62), pp.2973. ⟨10.21105/joss.02973⟩. ⟨hal-03765428⟩
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