Dendrimers, an Emerging Opportunity in Personalized Medicine? - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Personalized Medicine Année : 2022

Dendrimers, an Emerging Opportunity in Personalized Medicine?

Résumé

Dendrimers are highly branched macromolecules tailorable at will to fulfil precise requirements. They have generated a great many expectations and a huge number of publications and patents in relation to medicine, including in relation to personalized medicine, but have resulted in very poor clinical translation up to now. As clinical trials are the first steps in view of developing new compounds for (a personalized) medicine, this review focusses on the clinical trials carried out with dendrimers. Many of these clinical trials have been recently posted (2020–2022); thus, only very few concern phase 3. The safety and efficiency of essentially two main types of dendrimers, based on polylysine and polyamidoamide scaffolds, have been assessed up to now. These dendrimers were tested with the aim of treating mainly bacterial vaginosis, cancers, and COVID-19.
Fichier principal
Vignette du fichier
Caminade, Dendrimers, an Emerging Opportunity, 2022.pdf (2 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03760309 , version 1 (25-08-2022)

Licence

Paternité

Identifiants

Citer

Anne-Marie Caminade. Dendrimers, an Emerging Opportunity in Personalized Medicine?. Journal of Personalized Medicine, 2022, 12 (8), pp.1334. ⟨10.3390/jpm12081334⟩. ⟨hal-03760309⟩
57 Consultations
28 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More