Presentation of the CIRIL / radiation biology platform dedicated for experiments with the GANIL facility
Résumé
The CIRIL platform consists of a scientific coordinator, a technical staff, physicists and chemists, beam coordinators for all available beam lines (High, Medium and Low energy) and a radiation-biologist of the ARIA group, who serves as local contact for external users.
Beam times are selected and allocated according to specific scientific programs*, such as iPAC or CORA IBER. Further information about these programs are available online.
The radiation biology platform is devoted to the studies of ion beams effects on biological systems. The platform includes a comprehensive and state-of-the-art L2 cell culture room and a biochemistry laboratory, allowing hosted teams to perform various radiation biology experiments. Furthermore, the platform can be adapted for special requirements such as hypoxic conditions for example.
Irradiation with ion beams are performed at the GANIL facility, 50 m from the radiation biology platform, which makes the transfer of irradiated samples easy and quick. A remotely controlled sample holder allows the sequential irradiation of 23 windows of 25 cm2, including flasks, tubes and slides.
Most experiments are run with a carbon ion beam at a kinetic energy in the 100 MeV/u range (LET in water is about 25 keV/µm) at a low fluence (low dose) with about 104 to 108 particles/cm2. Other ion beams could be also delivered for specific requirements.
For each experiment, a dedicated team of physicists from the CIMAP laboratory is involved in the beam tuning and specific biological dosimetry [1].
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