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Article Dans Une Revue Natural Product Research Année : 2022

A new alkaloid and two organic acids from Portulaca oleracea L. and their bioactivities

Résumé

A new alkaloid, identified as 1-benzyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol, named oleraisoquinoline (1), and five organic acids and two esters, identified as 5-(hydroxymethyl)furan-2carboxylic acid (2), 1H-pyrrole-2,5-dicarboxylic acid (3), (7E,10E)-octadeca-7,10-dienoic acid (4), (10E,13E)-octadeca-10,13-dienoic acid (5), (7E,10E)-hexadeca-7,10-dienoic acid (6), methyl tridecanoate (7) and methyl (9E,12E)-octadeca-9,12-dienoate (8), were isolated from Portulaca oleracea L., among which compounds 2 and 4-7 were isolated for the first time. Moreover, the antiinflammatory activities of compounds 1-3 were studied, especially, compound 1 presented good inhibitory effects on the production of inflammatory factors IL-1β and TNF-α.
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Dates et versions

hal-03746681 , version 1 (05-08-2022)

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Peishan Liu, Xiujuan Lan, Xiaojun Tao, Jiayin Tian, Xixiang Ying, et al.. A new alkaloid and two organic acids from Portulaca oleracea L. and their bioactivities. Natural Product Research, In press, ⟨10.1080/14786419.2022.2103696⟩. ⟨hal-03746681⟩
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