Que sait-on de l’action des perturbateurs endocriniens sur le système immunitaire ? - Archive ouverte HAL
Article Dans Une Revue La Revue du Praticien Médecine Générale Année : 2021

What is known about the action of endocrine disruptors on the immune system?

Que sait-on de l’action des perturbateurs endocriniens sur le système immunitaire ?

Résumé

WHAT IS KNOWN ABOUT THE ACTION OF ENDOCRINE DISRUPTORS ON THE IMMUNE SYSTEM? The immune system (innate and adaptive immunity), involves different tissues and cell types to defend the body against external aggressions. This physiological mechanism involves some hormonal systems for its proper functioning. Moreover, new relationships between the immune system and endocrine processes have been recently described. Immunotoxicology is therefore a rapidly expanding field of research. Many environmental pollutants, such as organochlorine pesticides, polycyclic aromatic hydrocarbons or heavy metals, have an impact on the immune response leading either to a deficiency or a hyperactivation (autoimmune disease, allergy). More recently, other endocrine disruptors such as organofluorines are suspected to be immunotoxic. Low-level exposure to pollutants in the general population probably does not explain the development of all the pathologies, but it sentisizes organisms to the development of these pathologies, weakening certain key processes of the immune system.
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Dates et versions

hal-03744699 , version 1 (03-08-2022)

Identifiants

  • HAL Id : hal-03744699 , version 1
  • PUBMED : 34792908

Citer

Jérôme Estaquier, Étienne Blanc, Xavier Coumoul. Que sait-on de l’action des perturbateurs endocriniens sur le système immunitaire ?. La Revue du Praticien Médecine Générale, 2021, 71 (7), pp.729-734. ⟨hal-03744699⟩
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