Distal Construction of a Carbon‐SCF 2 R Bond on Aliphatic Alcohols Enabled by 1,5‐Hydrogen‐Atom Transfer
Résumé
An approach for the distal construction of a C(sp3)−SCF2R bond on aliphatic alcohols enabled by 1,5-hydrogen-atom transfer (HAT) was developed. In the presence of a hypervalent iodine (PIDA) and readily available ArSO2SCF2R reagents, this transition metal-free approach allowed the remote functionalization of a broad variety of alcohols with emergent and high added-value SCF2R moieties (R=H, F, CO2Et and PO(OEt)2) under blue light irradiation.
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Adv Synth Catal - 2022 - Petit‐Cancelier - Distal Construction of a Carbon‐SCF2R Bond on Aliphatic Alcohols Enabled by 1-1.pdf (3.54 Mo)
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