Synthesis of a library of SCF2CO2Et reagents: An access to original (ethoxycarbonyl)difluoromethylthioesters
Résumé
A library of original and shelf-stable reagents, source of the (ethoxycarbonyl)difluoromethylthio group, is reported. These reagents are applied to the functionalization of a large panel of aldehydes via a transition metal-free protocol under mild reaction conditions. This approach offers an efficient access to valuable difluoromethylthioester derivatives.
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