Open Modification Search using SpecOMS and i2MassChroQ
Résumé
SpecOMS is an Open Modification Search method published originally in David et al., 2017. SpecOMS compares experimental spectra generated by a discovery proteomics experiment to a whole set of theoretical spectra deduced from a protein database in a few minutes on a standard workstation. This allows the identification of unknown modification on peptides and reduces the proportion of undecided peptide spectrum matches compared to classical identification engines. We present here an evaluation of the SpecOMS accuracy to identify modified peptides and a dedicated graphical user interface that helps to browse and visualize peptides identified with this method.
Domaines
| Origine | Fichiers produits par l'(les) auteur(s) |
|---|---|
| Licence |