Monitoring the gelation of gellan gum with torsion rheometry and brightness-mode ultrasound - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Current Directions in Biomedical Engineering Année : 2022

Monitoring the gelation of gellan gum with torsion rheometry and brightness-mode ultrasound

Résumé

Gellan gum is a hydrogel with several applications in ultrasonic imaging, novel drug delivery, and tissue regeneration. As hydrogels are dynamic entities, their viscocelastic and therefore their acoustic properties change over time, which is of interest to monitor. To determine the speed of sound from brightness-mode images, however, rather large quantities of hydrogel are needed. In this study, we investigated torsion rheometry as a means to determine acoustic properties. Perceived speeds of sound were derived and computed from torsion rheometry measurements of gelating gellan gum mixed with spermidine trihydrochloride crosslinker. For comparison, brightness-mode ultrasonic images were recorded of the same material inside a phantom well. The rheometry data converged to a speed of sound within a standard devitation of the speed of sound measured from the brightness-mode images. We have shown that dynamic acoustic properties of gelating gellan gum can be simulated and experimentally determined using torsion rheometry.
Fichier principal
Vignette du fichier
10.1515_cdbme-2022-1010.pdf (1.03 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03696313 , version 1 (02-09-2022)

Licence

Paternité

Identifiants

Citer

Michiel Postema, Christine Gering, Nicole Anderton, Craig Stuart Carlson, Minna Kellomäki. Monitoring the gelation of gellan gum with torsion rheometry and brightness-mode ultrasound. Current Directions in Biomedical Engineering, 2022, Proceedings of the 2022 Joint Annual Conference of the Austrian (ÖGBMT), German (VDE DGBMT) and Swiss (SSBE) Societies for Biomedical Engineering, 8 (2), pp.33-36. ⟨10.1515/cdbme-2022-1010⟩. ⟨hal-03696313⟩
102 Consultations
21 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More