[Conduction defects as the presenting feature of sarcoidosis or observed during the course of the disease: regression with corticoid steroid therapy]. - Archive ouverte HAL
Article Dans Une Revue Archives des Maladies du Coeur et des Vaisseaux Année : 2003

[Conduction defects as the presenting feature of sarcoidosis or observed during the course of the disease: regression with corticoid steroid therapy].

M Berhouet
  • Fonction : Auteur
D Casset-Senon
  • Fonction : Auteur
V Lesire
  • Fonction : Auteur
T Farrokhi-Moshai
  • Fonction : Auteur
Laurent Fauchier
J Charniot
  • Fonction : Auteur
D Babuty
  • Fonction : Auteur
P Cosnay
  • Fonction : Auteur

Résumé

Cardiac sarcoidosis is often unrecognised because of the absence of specific clinical and electrical signs. The consequences are serious, the main risk being sudden death due to conduction defects (24 to 31% of cases) or ventricular arrhythmias. Any conduction defect without an obvious cause in a young patient should suggest a possible diagnosis of sarcoidosis. The confirmation is histological when giant cell non-caseuting epithelioid granuloma is demonstrated but myocardial biopsies are only positive in 20% of cases. Therefore, biopsy of accessible organs such as salivary glands is recommended. Diagnostic strategy consists in searching for signs of systemic sarcoidosis, and, when the diagnosis has been established, perform a complete work-up with echocardiography, dipyridamole myocardial scintigraphy, cardiac MRI and 24 hour ambulatory ECG recordings (Holter). The only proven treatment is steroid therapy with occasional spectacular observations of reversibility of arrhythmias or conduction defects.
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Dates et versions

hal-03679638 , version 1 (26-05-2022)

Identifiants

  • HAL Id : hal-03679638 , version 1
  • PUBMED : 12868351

Citer

M Berhouet, D Casset-Senon, M Machet, V Lesire, T Farrokhi-Moshai, et al.. [Conduction defects as the presenting feature of sarcoidosis or observed during the course of the disease: regression with corticoid steroid therapy].. Archives des Maladies du Coeur et des Vaisseaux, 2003, 96 (6), pp.677-82. ⟨hal-03679638⟩
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