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Article Dans Une Revue Mammalian Genome Année : 2017

Modeling human disease in rodents by CRISPR/Cas9 genome editing

Résumé

Modeling human disease has proven to be a challenge for the scientific community. For years, generating an animal model was complicated and restricted to very few species. With the rise of CRISPR/Cas9, it is now possible to generate more or less any animal model. In this review, we will show how this technology is and will change our way to obtain relevant disease animal models and how it should impact human health.

Domaines

Génétique

Dates et versions

hal-03679167 , version 1 (25-05-2022)

Identifiants

Citer

Marie-Christine Birling, Yann Herault, Guillaume Pavlovic. Modeling human disease in rodents by CRISPR/Cas9 genome editing. Mammalian Genome, 2017, 28, pp.291-301. ⟨10.1007/s00335-017-9703-x⟩. ⟨hal-03679167⟩
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