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Journal Articles Cell Chemical Biology Year : 2016

Eukaryotic Ribosome as a Target for Cardiovascular Disease

Abstract

Cardiovascular diseases have been associated with genetic variants and increased plasma level of the secreted protein PCSK9. In this issue of Cell Chemical Biology, Petersen et al. (2016) describe an inhibitor of PCSK9 secretion in human cells that, surprisingly, targets the 80S ribosome.
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inserm-01415698 , version 1 (13-12-2016)

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Simone P Pellegrino, Gulnara Yusupova. Eukaryotic Ribosome as a Target for Cardiovascular Disease. Cell Chemical Biology, 2016, 17 (23), pp.1319-1321. ⟨10.1016/j.chembiol.2016.11.004⟩. ⟨inserm-01415698⟩
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