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Article Dans Une Revue Organic Letters Année : 2005

Cycloruthenated Primary and Secondary Amines as Efficient Catalyst Precursors for Asymmetric Transfer Hydrogenation

Résumé

Ruthenacycles obtained by cyclometalation of enantiopure aromatic primary or secondary amines with [(η6-benzene)RuCl2]2 or with [(η6-p-cymene)RuCl2]2 are efficient catalysts for asymmetric transfer hydrogenation (TOF up to 190 h-1 at room temperature). Enantioselectivities in the transfer hydrogenation of acetophenone ranged from 38% to 89%. It is possible to prepare the catalysts in situ, which allows the use of high throughput experimentation.

Dates et versions

hal-03639855 , version 1 (13-04-2022)

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Citer

Jean-Baptiste Sortais, Vincent Ritleng, Adeline Voelklin, Alexandre Holuigue, Hakima Smail, et al.. Cycloruthenated Primary and Secondary Amines as Efficient Catalyst Precursors for Asymmetric Transfer Hydrogenation. Organic Letters, 2005, 7 (7), pp.1247-1250. ⟨10.1021/ol047353d⟩. ⟨hal-03639855⟩

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