Tinnitus Perception in Light of a Parietal Operculo–Insular Involvement: A Review - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Brain Sciences Année : 2022

Tinnitus Perception in Light of a Parietal Operculo–Insular Involvement: A Review

Résumé

In tinnitus literature, researchers have increasingly been advocating for a clearer distinction between tinnitus perception and tinnitus-related distress. In non-bothersome tinnitus, the perception itself can be more specifically investigated: this has provided a body of evidence, based on resting-state and activation fMRI protocols, highlighting the involvement of regions outside the conventional auditory areas, such as the right parietal operculum. Here, we aim to conduct a review of available investigations of the human parietal operculo–insular subregions conducted at the microscopic, mesoscopic, and macroscopic scales arguing in favor of an auditory–somatosensory cross-talk. Both the previous literature and new results on functional connectivity derived from cortico–cortical evoked potentials show that these subregions present a dense tissue of interconnections and a strong connectivity with auditory and somatosensory areas in the healthy brain. Disrupted integration processes between these modalities may thus result in erroneous perceptions, such as tinnitus. More precisely, we highlight the role of a subregion of the right parietal operculum, known as OP3 according to the Jülich atlas, in the integration of auditory and somatosensory representation of the orofacial muscles in the healthy population. We further discuss how a dysfunction of these muscles could induce hyperactivity in the OP3. The evidence of direct electrical stimulation of this area eliciting auditory hallucinations further suggests its involvement in tinnitus perception. Finally, a small number of neuroimaging studies of therapeutic interventions for tinnitus provide additional evidence of right parietal operculum involvement.

Domaines

Neurosciences
Fichier principal
Vignette du fichier
Tinnitus Perception in Light of a Parietal Operculo–Insular Involvement_ A Review _ Enhanced Reader.pdf (11.12 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03634336 , version 1 (07-04-2022)

Licence

Paternité

Identifiants

Citer

Chloé Jaroszynski, Agnès Job, Maciej Jedynak, Olivier David, Chantal Delon-Martin. Tinnitus Perception in Light of a Parietal Operculo–Insular Involvement: A Review. Brain Sciences, 2022, 12 (3), pp.334. ⟨10.3390/brainsci12030334⟩. ⟨hal-03634336⟩
38 Consultations
14 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More