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                <term xml:lang="en">Prevalence</term>
                <term xml:lang="en">Non-response</term>
                <term xml:lang="en">Selection bias</term>
                <term xml:lang="en">Medico-administrative databases</term>
                <term xml:lang="fr">Prévalence</term>
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                <term xml:lang="fr">Non-réponse</term>
                <term xml:lang="fr">Pondération</term>
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              <p>INTRODUCTION – CONSTANCES is a general purpose epidemiological cohort with analytical as well as descriptive objectives. AIM – To estimate prevalences which can be extrapolated to people aged 30 to 69 in 2013, within the scope of CONSTANCES by taking into account non-participation and combining two years of invitation. METHODS – From a sample of invited subjects selected randomly in 2012  and 2013  and aged 30  to 69  years (n=471,152), participation was studied as a function of sociodemographic data, as well as data from the SNIIRAM (national inter-scheme health insurance information system) and the CNAV (National Old-Age Insurance Fund). Different sex-speciﬁc prevalences were estimated by reweighting: ﬁrstly, without accounting for non- participation, and secondly, accounting for non-participation using sociodemographic, SNIIRAM and CNAV data. RESULTS – The participation rate is 7.3%. Many variables from SNIIRAM and CNAV are associated with participa-tion in the CONSTANCES cohort. A comparison of prevalences shows that taking non-participation into account has a low to important impact, whose direction can differ, whether the variables are measured at the health examination center or collected by self-administered questionnaire. CONCLUSION – These preliminary results show that the contribution of SNIIRAM and CNAV data is important in order to study the selection effects in the cohort, and that it is generally required to take them into account to estimate prevalences. The combination of years of invitation should be conducted with caution.</p>
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              <p>Introduction-Constances est une cohorte épidémiologique généraliste avec des objectifs analytiques et descriptifs. Objectif-Estimer des prévalences extrapolables aux personnes âgées entre 30 et 69 ans en 2013 entrant dans le champ de Constances, en prenant en compte la non-participation et en combinant deux années d'invitation. Méthodes-À partir des invités tirés au sort en 2012 et 2013 âgés de 30 à 69 ans (n=471 152), la participation est étudiée en fonction des données sociodémographiques, des données du Sniiram (Système national d'information inter-régimes de l'Assurance maladie) et de celles de la Cnav (Caisse nationale d'assurance vieillesse). Plusieurs prévalences sont estimées selon le sexe par repondération : sans prise en compte de la non-participation, puis en prenant en compte la non-participation via les données sociodémographiques, du Sniiram et de la Cnav. Résultats-Le taux de participation est de 7,3%. De nombreuses variables du Sniiram et de la Cnav sont associées à la participation dans Constances. La comparaison des prévalences montre que la prise en compte de la non-participation a un impact faible à important, dont le sens peut différer, que ce soit pour des variables mesurées au Centre d'examen de santé ou par auto-questionnaire. Conclusion-Ces résultats préliminaires montrent que l'apport des données du Sniiram et de la Cnav est important pour étudier les effets de sélection dans Constances et qu'il est en général nécessaire de les prendre en compte pour estimer des prévalences. La combinaison des années d'invitation est à réaliser avec précaution.</p>
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