Journal Articles BMC Medicine Year : 2022

Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level

Sophie Meakin
  • Function : Author
Sam Abbott
  • Function : Author
Nikos Bosse
  • Function : Author
James Munday
  • Function : Author
Joel Hellewell
  • Function : Author
Katharine Sherratt
  • Function : Author
Lloyd Chapman
  • Function : Author
Kiesha Prem
  • Function : Author
Petra Klepac
  • Function : Author
Thibaut Jombart
  • Function : Author
Gwenan Knight
  • Function : Author
Yalda Jafari
  • Function : Author
Stefan Flasche
  • Function : Author
William Waites
  • Function : Author
Mark Jit
  • Function : Author
Rosalind Eggo
  • Function : Author
C. Julian Villabona-Arenas
  • Function : Author
Timothy Russell
  • Function : Author
Graham Medley
  • Function : Author
W. John Edmunds
  • Function : Author
Nicholas Davies
  • Function : Author
Yang Liu
  • Function : Author
Stéphane Hué
  • Function : Author
Oliver Brady
  • Function : Author
Rachael Pung
  • Function : Author
Kaja Abbas
  • Function : Author
Amy Gimma
  • Function : Author
Paul Mee
  • Function : Author
Akira Endo
  • Function : Author
Samuel Clifford
  • Function : Author
Fiona Yueqian Sun
  • Function : Author
Ciara Mccarthy
  • Function : Author
Billy Quilty
  • Function : Author
Alicia Rosello
  • Function : Author
Frank Sandmann
  • Function : Author
Rosanna Barnard
  • Function : Author
Adam Kucharski
  • Function : Author
Simon Procter
  • Function : Author
Christopher Jarvis
  • Function : Author
Hamish Gibbs
  • Function : Author
David Hodgson
  • Function : Author
Rachel Lowe
Katherine Atkins
  • Function : Author
Mihaly Koltai
  • Function : Author
Carl Pearson
  • Function : Author
Emilie Finch
  • Function : Author
Kerry Wong
  • Function : Author
Matthew Quaife
  • Function : Author
Kathleen O’reilly
  • Function : Author
Damien Tully
  • Function : Author
Sebastian Funk

Abstract

Background: Forecasting healthcare demand is essential in epidemic settings, both to inform situational awareness and facilitate resource planning. Ideally, forecasts should be robust across time and locations. During the COVID-19 pandemic in England, it is an ongoing concern that demand for hospital care for COVID-19 patients in England will exceed available resources. Methods: We made weekly forecasts of daily COVID-19 hospital admissions for National Health Service (NHS) Trusts in England between August 2020 and April 2021 using three disease-agnostic forecasting models: a mean ensemble of autoregressive time series models, a linear regression model with 7-day-lagged local cases as a predictor, and a scaled convolution of local cases and a delay distribution. We compared their point and probabilistic accuracy to a mean-ensemble of them all and to a simple baseline model of no change from the last day of admissions. We measured predictive performance using the weighted interval score (WIS) and considered how this changed in different scenarios (the length of the predictive horizon, the date on which the forecast was made, and by location), as well as how much admissions forecasts improved when future cases were known. Results: All models outperformed the baseline in the majority of scenarios. Forecasting accuracy varied by forecast date and location, depending on the trajectory of the outbreak, and all individual models had instances where they were the top- or bottom-ranked model. Forecasts produced by the mean-ensemble were both the most accurate and most consistently accurate forecasts amongst all the models considered. Forecasting accuracy was improved when using future observed, rather than forecast, cases, especially at longer forecast horizons. Conclusions: Assuming no change in current admissions is rarely better than including at least a trend. Using confirmed COVID-19 cases as a predictor can improve admissions forecasts in some scenarios, but this is variable and depends on the ability to make consistently good case forecasts. However, ensemble forecasts can make forecasts that make consistently more accurate forecasts across time and locations. Given minimal requirements on data and computation, our admissions forecasting ensemble could be used to anticipate healthcare needs in future epidemic or pandemic settings.

Dates and versions

hal-03596660 , version 1 (03-03-2022)

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Sophie Meakin, Sam Abbott, Nikos Bosse, James Munday, Hugo Gruson, et al.. Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local level. BMC Medicine, 2022, 20 (1), pp.86. ⟨10.1186/s12916-022-02271-x⟩. ⟨hal-03596660⟩
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