Abstract This study reports a comparative analysis of the environmental conditions and micro-seismicity recorded on a rock wall resulting from an intense meteorological event. The findings are focused on a quarry wall located in the Acuto Field Laboratory (Central Italy), where multi-parametric environmental monitoring is operating and an Artificial intelligence Camera Prototype has been placed to detect rock falls reaching a railway target. Six accelerometers were installed to detect micro-seismic events caused by the expected strong thermal transient caused by the Buran storm on February 2018. Within a few hours, a steep decrease in the average air and rock mass temperature down to 8 °C was recorded, and −4 °C and −8 °C were reached for the rock and air temperatures, respectively. A total of 103 micro-seismic events were analysed with respect to both rainfall and thermal forcing: while no correlation with rainfall was reported, the steep thermal transient was responsible for the strain effect that occurred during the heating phase of the rock mass following the Buran storm. An elastic deformation event with a maximum daily amplitude of 165 μ strain was recorded by the strain gages installed on the mm-joints due to the rock heating and cooling caused by the variation in temperature. The collected evidences show the relevance of short thermal transients in modifying stress conditions within rock masses and their relationship to a peculiar micro-seismic response. The main outcomes established the key role played by integrated monitoring systems to better understand the relationship between vibrational behaviour and environmental forcings in terms of understanding the precursors to rock failure.