Article Dans Une Revue Fitoterapia Année : 2020

Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens

Résumé

Five new cassane-type diterpenoid heterosides, i. e. two cassane-type amides (1–2), two erythrophlamine-type amine esters (3–4) and a non‑nitrogenous erythrophlamine analogue (5) were isolated from the root barks (1–2) and the seeds (3–5) of Erythrophleum suaveolens. Their structures were unambiguously established by interpretation of their HRESIMS, 1D and 2D NMR data, and chemical degradation for sugar determination. Compounds 3–5 were evaluated for their cytotoxicity against a panel of three cell lines, revealing modest to strong activities.

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hal-03492054 , version 1 (22-08-2022)

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Ahmont Claude Landry Kablan, Jacques Dibi Konan, Gustav Komlaga, Faustin Aka Kabran, Ballo Daouda, et al.. Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens. Fitoterapia, 2020, 146, pp.104700 -. ⟨10.1016/j.fitote.2020.104700⟩. ⟨hal-03492054⟩
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