Abstract The long fascination that antiferromagnetic materials has exerted on the scientific community over about a century has been entirely renewed recently with the discovery of several unexpected phenomena, including various classes of anomalous spin and charge Hall effects and unconventional magnonic transport, and also homochiral magnetic entities such as skyrmions. With these breakthroughs, antiferromagnets stand out as a rich playground for the investigation of novel topological behavior, and as promising candidate materials for disruptive low-power microelectronic applications. Remarkably, the newly discovered phenomena are all related to the topology of the magnetic, electronic or magnonic ground state of the antiferromagnets. This review exposes how non-trivial topology emerges at different levels in antiferromagnets and explores the novel mechanisms that have been discovered recently. We also discuss how novel classes of quantum magnets could enrich the currently expanding field of antiferromagnetic spintronics and how spin transport can in turn favor a better understanding of exotic quantum excitations.