Time from first seen in specialist care to surgery does not influence survival outcome in patients with upfront resected pancreatic adenocarcinoma - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue BMC Surgery Année : 2021

Time from first seen in specialist care to surgery does not influence survival outcome in patients with upfront resected pancreatic adenocarcinoma

B. Royer
  • Fonction : Auteur

Résumé

Background: This study evaluated the impact of time to surgery (TTS) on overall survival (OS), disease free survival (DFS) and postoperative complication rate in patients with upfront resected pancreatic adenocarcinoma (PA). Methods: We retrospectively included patients who underwent upfront surgery for PA between January 1, 2004 and December 31, 2014 from four French centers. TTS was defined as the number of days between the date of the first consultation in specialist care and the date of surgery. DFS for a 14-day TTS was the primary endpoint. We also analyzed survival depending on different delay cut-offs (7, 14, 28, 60 and 75 days). Results: A total of 168 patients were included. 59 patients (35%) underwent an upfront surgery within 14 days. Patients in the higher delay group (> 14 days) had significantly more vein resections and endoscopic biliary drainage. Adjusted OS (p = 0.44), DFS (p = 0.99), fistulas (p = 0.41), hemorrhage (p = 0.59) and severe post-operative complications (p = 0.82) were not different according to TTS (> 14 days). Other delay cut-offs had no impact on OS or DFS. Discussion: TTS seems to have no impact on OS, DFS and 90-day postoperative morbidity.
Fichier principal
Vignette du fichier
s12893-021-01409-7.pdf (1.24 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03487733 , version 1 (01-02-2022)

Licence

Paternité

Identifiants

Citer

Mathias Brugel, Olivier Bouché, Réza Kianmanesh, Lugdivine Teuma, Ahmad Tashkandi, et al.. Time from first seen in specialist care to surgery does not influence survival outcome in patients with upfront resected pancreatic adenocarcinoma. BMC Surgery, 2021, 21 (1), pp.413. ⟨10.1186/s12893-021-01409-7⟩. ⟨hal-03487733⟩
21 Consultations
18 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More