Suppose $X$ is a smooth complex algebraic variety. A necessary condition for a complex topological vector bundle on $X$ (viewed as a complex manifold) to be algebraic is that all Chern classes must be algebraic cohomology classes, i.e., lie in the image of the cycle class map. We analyze the question of whether algebraicity of Chern classes is sufficient to guarantee algebraizability of complex topological vector bundles. For affine varieties of dimension $\leq 3$, it is known that algebraicity of Chern classes of a vector bundle guarantees algebraizability of the vector bundle. In contrast, we show in dimension $\geq 4$ that algebraicity of Chern classes is insufficient to guarantee algebraizability of vector bundles. To do this, we construct a new obstruction to algebraizability using Steenrod operations on Chow groups. By means of an explicit example, we observe that our obstruction is non-trivial in general.