Comparison of a novel high-throughput screening system with the Bottle assay for evaluating insecticide toxicity - Archive ouverte HAL
Article Dans Une Revue Journal of Pesticide Science Année : 2009

Comparison of a novel high-throughput screening system with the Bottle assay for evaluating insecticide toxicity

Résumé

Insecticide toxicity is commonly evaluated for disease vectors by either the WHO test or Bottle assay. More recently, a high-throughput screening (HTS) system was developed for testing insecticide effects on mosquito behavior and mortality. We compared HTS with the Bottle assay to evaluate the toxicity of insecticides in a population of Aedes aegypti from Thailand. Both the HTS and Bottle assay system were determined to be equivalent. The two systems mainly differed (1) in reaction time, with mosquitoes reacting faster in the Bottle assay than HTS, (2) in knock-down and mortality at low doses. This information will guide the testing protocol for evaluating chemical effects on behavioral responses in various vector populations
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Dates et versions

hal-03433441 , version 1 (17-11-2021)

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Isabelle Dusfour, Nicole L Achee, Michael R Sardelis, Theeraphap Chareonviriyaphap, John P Grieco. Comparison of a novel high-throughput screening system with the Bottle assay for evaluating insecticide toxicity. Journal of Pesticide Science, 2009, 34 (4), pp.283 - 286. ⟨10.1584/jpestics.g09-22⟩. ⟨hal-03433441⟩
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