The factors and dynamics that initiated the Neolithisation process in the South Caucasus between the very end of the 7th and the beginning of the 6th millennium BCEare still unclear and hotly debated. It is within this framework that the excavations at Kiçik Tepe, in the middle Kura river valley of Western Azerbaijan, aim to offer new data and new perspectives on the complex interplay of environmental, social and cultural factors that contributed to this process. Excavations at Kiçik Tepe uncovered two main phases of occupation consisting of circular buildings dating to the first centuries of the 6th millennium. Architectural remains allowed us to highlight an evolutionary architectural trajectory hinting at social and productive changes in the role and structure of the households. The subsistence strategies that rely on species domesticated elsewhere show at once a series of specificities highlighting adaptation to the local environment and the exploitation of wild species possibly resulting from previous Mesolithic practices. Simultaneously, while the almost aceramic way of life at Kiçik Tepe outlines a local dialectic between Mesolithic and Neolithic cooking practices, lithic and macrolithic tools pinpoint broadly shared regional elements as well as very localised traits framed into both long and short distance contacts. As a whole the new evidence from Kiçik Tepe highlights that the Neolithisation in the South Caucasus was not a straightforward process that consisted of the abrupt and homogenous adoption of an exogenous 'package' but most probably of a gradual and complex process of change resulting from dynamics of resistance and innovation between old and new socioeconomic and cultural models.