<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-03430888</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-26T01:06:11+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes</title>
            <author role="aut">
              <persName>
                <forename type="first">Anne-Marie</forename>
                <surname>Ruppert</surname>
              </persName>
              <idno type="halauthorid">315777-0</idno>
              <affiliation ref="#struct-542158"/>
              <affiliation ref="#struct-328304"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michèle</forename>
                <surname>Beau-Faller</surname>
              </persName>
              <idno type="halauthorid">315776-0</idno>
              <affiliation ref="#struct-211628"/>
              <affiliation ref="#struct-528129"/>
              <affiliation ref="#struct-543256"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Didier</forename>
                <surname>Debieuvre</surname>
              </persName>
              <idno type="halauthorid">361834-0</idno>
              <affiliation ref="#struct-574507"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">L'Houcine</forename>
                <surname>Ouafik</surname>
              </persName>
              <email type="md5">06186d27f3781dae0040be78f05b8573</email>
              <email type="domain">univ-amu.fr</email>
              <idno type="idhal" notation="string">l-houcine-ouafik</idno>
              <idno type="idhal" notation="numeric">17794</idno>
              <idno type="halauthorid" notation="string">12877-17794</idno>
              <idno type="IDREF">https://www.idref.fr/03307741X</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4848-1232</idno>
              <affiliation ref="#struct-527029"/>
              <affiliation ref="#struct-484894"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Virginie</forename>
                <surname>Westeel</surname>
              </persName>
              <idno type="idhal" notation="numeric">760640</idno>
              <idno type="halauthorid" notation="string">367156-760640</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-2358-3694</idno>
              <affiliation ref="#struct-300165"/>
              <affiliation ref="#struct-182215"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Isabelle</forename>
                <surname>Rouquette</surname>
              </persName>
              <idno type="halauthorid">649003-0</idno>
              <affiliation ref="#struct-450027"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Julien</forename>
                <surname>Mazières</surname>
              </persName>
              <email type="md5">5fc5b0b2eb82d644afecc289fe088c4b</email>
              <email type="domain">chu-toulouse.fr</email>
              <idno type="idhal" notation="numeric">1033301</idno>
              <idno type="halauthorid" notation="string">361837-1033301</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5921-7613</idno>
              <affiliation ref="#struct-208500"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierre-Paul</forename>
                <surname>Bringuier</surname>
              </persName>
              <idno type="halauthorid">696896-0</idno>
              <affiliation ref="#struct-212722"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Isabelle</forename>
                <surname>Monnet</surname>
              </persName>
              <idno type="halauthorid">180747-0</idno>
              <affiliation ref="#struct-433319"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Fabienne</forename>
                <surname>Escande</surname>
              </persName>
              <idno type="halauthorid">242098-0</idno>
              <affiliation ref="#struct-534830"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Charles</forename>
                <surname>Ricordel</surname>
              </persName>
              <idno type="idhal" notation="numeric">772291</idno>
              <idno type="halauthorid" notation="string">859601-772291</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6160-2732</idno>
              <affiliation ref="#struct-1090097"/>
              <affiliation ref="#struct-301327"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Philippe</forename>
                <surname>Merlio</surname>
              </persName>
              <idno type="idhal" notation="numeric">764190</idno>
              <idno type="halauthorid" notation="string">554602-764190</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0305-0850</idno>
              <idno type="IDREF">https://www.idref.fr/060916028</idno>
              <affiliation ref="#struct-259761"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Henri</forename>
                <surname>Janicot</surname>
              </persName>
              <idno type="halauthorid">465088-0</idno>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Antoinette</forename>
                <surname>Lemoine</surname>
              </persName>
              <idno type="halauthorid">316032-0</idno>
              <affiliation ref="#struct-552263"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pascal</forename>
                <surname>Foucher</surname>
              </persName>
              <idno type="halauthorid">447349-0</idno>
              <affiliation ref="#struct-300924"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michel</forename>
                <surname>Poudenx</surname>
              </persName>
              <idno type="halauthorid">648980-0</idno>
              <affiliation ref="#struct-123026"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Franck</forename>
                <surname>Morin</surname>
              </persName>
              <idno type="halauthorid">361838-0</idno>
              <affiliation ref="#struct-81952"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alexandra</forename>
                <surname>Langlais</surname>
              </persName>
              <idno type="halauthorid">19263-0</idno>
              <affiliation ref="#struct-81952"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierre-Jean</forename>
                <surname>Souquet</surname>
              </persName>
              <idno type="halauthorid">361840-0</idno>
              <affiliation ref="#struct-205255"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Fabrice</forename>
                <surname>Barlesi</surname>
              </persName>
              <email type="md5">c946260ef10727ff875cb46bcd062088</email>
              <email type="domain">ap-hm.fr</email>
              <idno type="idhal" notation="numeric">1357222</idno>
              <idno type="halauthorid" notation="string">361833-1357222</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5793-3539</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/O-1706-2017</idno>
              <idno type="IDREF">https://www.idref.fr/087602997</idno>
              <idno type="VIAF">https://viaf.org/viaf/107060160</idno>
              <idno type="ISNI">http://isni.org/isni/0000000077046200</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/O-1706-2017</idno>
              <affiliation ref="#struct-536855"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Wislez</surname>
              </persName>
              <email type="md5">36fd731988583d1e60ec4bb0d07569ac</email>
              <email type="domain">tnn.aphp.fr</email>
              <idno type="idhal" notation="numeric">1311560</idno>
              <idno type="halauthorid" notation="string">561129-1311560</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7518-7859</idno>
              <idno type="IDREF">https://www.idref.fr/089425774</idno>
              <idno type="VIAF">https://viaf.org/viaf/214239980</idno>
              <idno type="ISNI">http://isni.org/isni/0000000139470155</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=T3vtJXAAAAAJ</idno>
              <affiliation ref="#struct-18189"/>
              <affiliation ref="#struct-1004777"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>L'Houcine</forename>
                <surname>Ouafik</surname>
              </persName>
              <email type="md5">06186d27f3781dae0040be78f05b8573</email>
              <email type="domain">univ-amu.fr</email>
            </editor>
            <funder>AstraZeneca</funder>
            <funder>Roche</funder>
            <funder>2011-038, Institut National Du Cancer, France</funder>
            <funder>Novartis, France</funder>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2021-11-16 14:17:33</date>
              <date type="whenModified">2026-05-13 03:14:37</date>
              <date type="whenReleased">2021-11-25 09:53:40</date>
              <date type="whenProduced">2020-09</date>
              <date type="whenEndEmbargoed">2021-11-16</date>
              <ref type="file" target="https://amu.hal.science/hal-03430888v1/document">
                <date notBefore="2021-11-16"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://amu.hal.science/hal-03430888v1/file/PIIS2666364320300576.pdf" id="file-3430888-3023530">
                <date notBefore="2021-11-16"/>
              </ref>
              <ref type="externalLink" target="http://www.jtocrr.org/article/S2666364320300576/pdf"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="118798">
                <persName>
                  <forename>L'Houcine</forename>
                  <surname>Ouafik</surname>
                </persName>
                <email type="md5">06186d27f3781dae0040be78f05b8573</email>
                <email type="domain">univ-amu.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-03430888</idno>
            <idno type="halUri">https://amu.hal.science/hal-03430888</idno>
            <idno type="halBibtex">ruppert:hal-03430888</idno>
            <idno type="halRefHtml">&lt;i&gt;JTO Clinical and Research Reports&lt;/i&gt;, 2020, 1 (3), pp.100052. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.jtocrr.2020.100052"&gt;&amp;#x27E8;10.1016/j.jtocrr.2020.100052&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">JTO Clinical and Research Reports, 2020, 1 (3), pp.100052. &amp;#x27E8;10.1016/j.jtocrr.2020.100052&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by-nc-nd/4.0/">CC BY-NC-ND 4.0 - Attribution - Non-commercial use - No Derivative Works<ref corresp="#file-3430888-3023530"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="EPHE">École Pratique des Hautes Études</idno>
            <idno type="stamp" n="UNIV-TLSE3">Université de Toulouse</idno>
            <idno type="stamp" n="UNIV-RENNES1">Université de Rennes 1</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-AMU">Aix Marseille Université</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="UNIV-STRASBG">Université de Strasbourg</idno>
            <idno type="stamp" n="CHLS" corresp="HCL">Centre Hospitalier Lyon Sud</idno>
            <idno type="stamp" n="FNCLCC" corresp="INSERM">UNICANCER</idno>
            <idno type="stamp" n="LACASSAGNE" corresp="FNCLCC">Centre Antoine Lacassagne</idno>
            <idno type="stamp" n="MARQUIS" corresp="FNCLCC">Centre Eugène Marquis</idno>
            <idno type="stamp" n="STRAUSS" corresp="FNCLCC">Centre Paul Strauss</idno>
            <idno type="stamp" n="HL">Publications CHU Rennes</idno>
            <idno type="stamp" n="CORDELIERS" corresp="SORBONNE-UNIVERSITE">Centre de recherche des Cordeliers</idno>
            <idno type="stamp" n="OSS">Chemistry Oncogenesis Stress Signaling</idno>
            <idno type="stamp" n="UR1-UFR-SVE">UFR SVE Sciences de la vie et de l'environnement</idno>
            <idno type="stamp" n="UR1-HAL">Publications labos UR1 dans HAL-Rennes 1</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="UR1-SDV">UR1 - publications SDV</idno>
            <idno type="stamp" n="UNIV-COTEDAZUR">Université Côte d'Azur</idno>
            <idno type="stamp" n="INP">Institut de Neurophysiopathologie</idno>
            <idno type="stamp" n="TEST-UR-CSS">TEST Université de Rennes CSS</idno>
            <idno type="stamp" n="SITE-ALSACE">Archive ouverte du site Alsace</idno>
            <idno type="stamp" n="UNIV-RENNES">Université de Rennes</idno>
            <idno type="stamp" n="INP-ATME">Angiogenesis and tumor MicroEnvironment</idno>
            <idno type="stamp" n="SORBONNE-UNIVERSITE">Sorbonne Université</idno>
            <idno type="stamp" n="SORBONNE-UNIV" corresp="SORBONNE-UNIVERSITE">Sorbonne Université 01/01/2018</idno>
            <idno type="stamp" n="SU-MEDECINE" corresp="SORBONNE-UNIVERSITE">Faculté de Santé de Sorbonne Université</idno>
            <idno type="stamp" n="SU-SCIENCES" corresp="SORBONNE-UNIVERSITE">Faculté des Sciences de Sorbonne Université</idno>
            <idno type="stamp" n="TEST-DEV">TEST-DEV</idno>
            <idno type="stamp" n="SU-MED" corresp="SORBONNE-UNIVERSITE">Médecine - Sorbonne Université</idno>
            <idno type="stamp" n="CHU-CLERMONTFERRAND">CHU DE CLERMONT FERRAND</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UNIVERSITE-PARIS" corresp="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UP-SANTE">Université Paris Cité - Faculté de Santé</idno>
            <idno type="stamp" n="TEST-HALCNRS">Collection test HAL CNRS</idno>
            <idno type="stamp" n="EPHE-PSL" corresp="PSL">École Pratique des Hautes Études - PSL</idno>
            <idno type="stamp" n="SU-TI">Sorbonne Université - Texte Intégral</idno>
            <idno type="stamp" n="UR1-BIO-SA">Pôle UnivRennes - Biologie-Santé</idno>
            <idno type="stamp" n="NEUROMARSEILLE">NeuroMarseille</idno>
            <idno type="stamp" n="ALLIANCE-SU"> Alliance Sorbonne Université</idno>
            <idno type="stamp" n="UNIV-UT3">Université Toulouse 3</idno>
            <idno type="stamp" n="UT3-INP">Université de Toulouse / Toulouse INP</idno>
            <idno type="stamp" n="UT3-TOULOUSEINP">Université de Toulouse / Toulouse INP</idno>
            <idno type="stamp" n="UNIV-COTEDAZUR_COLLECTION_DEFAUT">UNIV-COTEDAZUR_COLLECTION_DEFAUT</idno>
            <idno type="stamp" n="SUPRA_BIOLOGIE">Biologie hors MNHN &amp; stations</idno>
            <idno type="stamp" n="GRC4" corresp="SORBONNE-UNIVERSITE">Biomarqueurs Théranostiques des Cancers Bronchiques Non à Petites Cellules - Theranoscan</idno>
            <idno type="stamp" n="UNIVERSITE-BORDEAUX">Université de Bordeaux</idno>
            <idno type="stamp" n="UNIVOAK">UNIVOAK</idno>
            <idno type="stamp" n="TEST-NICE">test nice</idno>
            <idno type="stamp" n="UMR1260">NanoMédecine Régénérative (RNM) - UMR_S 1260</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne-Marie</forename>
                    <surname>Ruppert</surname>
                  </persName>
                  <idno type="halauthorid">315777-0</idno>
                  <affiliation ref="#struct-542158"/>
                  <affiliation ref="#struct-328304"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michèle</forename>
                    <surname>Beau-Faller</surname>
                  </persName>
                  <idno type="halauthorid">315776-0</idno>
                  <affiliation ref="#struct-211628"/>
                  <affiliation ref="#struct-528129"/>
                  <affiliation ref="#struct-543256"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Didier</forename>
                    <surname>Debieuvre</surname>
                  </persName>
                  <idno type="halauthorid">361834-0</idno>
                  <affiliation ref="#struct-574507"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">L'Houcine</forename>
                    <surname>Ouafik</surname>
                  </persName>
                  <email type="md5">06186d27f3781dae0040be78f05b8573</email>
                  <email type="domain">univ-amu.fr</email>
                  <idno type="idhal" notation="string">l-houcine-ouafik</idno>
                  <idno type="idhal" notation="numeric">17794</idno>
                  <idno type="halauthorid" notation="string">12877-17794</idno>
                  <idno type="IDREF">https://www.idref.fr/03307741X</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4848-1232</idno>
                  <affiliation ref="#struct-527029"/>
                  <affiliation ref="#struct-484894"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Virginie</forename>
                    <surname>Westeel</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">760640</idno>
                  <idno type="halauthorid" notation="string">367156-760640</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-2358-3694</idno>
                  <affiliation ref="#struct-300165"/>
                  <affiliation ref="#struct-182215"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Isabelle</forename>
                    <surname>Rouquette</surname>
                  </persName>
                  <idno type="halauthorid">649003-0</idno>
                  <affiliation ref="#struct-450027"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Julien</forename>
                    <surname>Mazières</surname>
                  </persName>
                  <email type="md5">5fc5b0b2eb82d644afecc289fe088c4b</email>
                  <email type="domain">chu-toulouse.fr</email>
                  <idno type="idhal" notation="numeric">1033301</idno>
                  <idno type="halauthorid" notation="string">361837-1033301</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5921-7613</idno>
                  <affiliation ref="#struct-208500"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierre-Paul</forename>
                    <surname>Bringuier</surname>
                  </persName>
                  <idno type="halauthorid">696896-0</idno>
                  <affiliation ref="#struct-212722"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Isabelle</forename>
                    <surname>Monnet</surname>
                  </persName>
                  <idno type="halauthorid">180747-0</idno>
                  <affiliation ref="#struct-433319"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Fabienne</forename>
                    <surname>Escande</surname>
                  </persName>
                  <idno type="halauthorid">242098-0</idno>
                  <affiliation ref="#struct-534830"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Charles</forename>
                    <surname>Ricordel</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">772291</idno>
                  <idno type="halauthorid" notation="string">859601-772291</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6160-2732</idno>
                  <affiliation ref="#struct-1090097"/>
                  <affiliation ref="#struct-301327"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Philippe</forename>
                    <surname>Merlio</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">764190</idno>
                  <idno type="halauthorid" notation="string">554602-764190</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0305-0850</idno>
                  <idno type="IDREF">https://www.idref.fr/060916028</idno>
                  <affiliation ref="#struct-259761"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Henri</forename>
                    <surname>Janicot</surname>
                  </persName>
                  <idno type="halauthorid">465088-0</idno>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Antoinette</forename>
                    <surname>Lemoine</surname>
                  </persName>
                  <idno type="halauthorid">316032-0</idno>
                  <affiliation ref="#struct-552263"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pascal</forename>
                    <surname>Foucher</surname>
                  </persName>
                  <idno type="halauthorid">447349-0</idno>
                  <affiliation ref="#struct-300924"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michel</forename>
                    <surname>Poudenx</surname>
                  </persName>
                  <idno type="halauthorid">648980-0</idno>
                  <affiliation ref="#struct-123026"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Franck</forename>
                    <surname>Morin</surname>
                  </persName>
                  <idno type="halauthorid">361838-0</idno>
                  <affiliation ref="#struct-81952"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alexandra</forename>
                    <surname>Langlais</surname>
                  </persName>
                  <idno type="halauthorid">19263-0</idno>
                  <affiliation ref="#struct-81952"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierre-Jean</forename>
                    <surname>Souquet</surname>
                  </persName>
                  <idno type="halauthorid">361840-0</idno>
                  <affiliation ref="#struct-205255"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Fabrice</forename>
                    <surname>Barlesi</surname>
                  </persName>
                  <email type="md5">c946260ef10727ff875cb46bcd062088</email>
                  <email type="domain">ap-hm.fr</email>
                  <idno type="idhal" notation="numeric">1357222</idno>
                  <idno type="halauthorid" notation="string">361833-1357222</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5793-3539</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/O-1706-2017</idno>
                  <idno type="IDREF">https://www.idref.fr/087602997</idno>
                  <idno type="VIAF">https://viaf.org/viaf/107060160</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000077046200</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/O-1706-2017</idno>
                  <affiliation ref="#struct-536855"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Wislez</surname>
                  </persName>
                  <email type="md5">36fd731988583d1e60ec4bb0d07569ac</email>
                  <email type="domain">tnn.aphp.fr</email>
                  <idno type="idhal" notation="numeric">1311560</idno>
                  <idno type="halauthorid" notation="string">561129-1311560</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7518-7859</idno>
                  <idno type="IDREF">https://www.idref.fr/089425774</idno>
                  <idno type="VIAF">https://viaf.org/viaf/214239980</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000139470155</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=T3vtJXAAAAAJ</idno>
                  <affiliation ref="#struct-18189"/>
                  <affiliation ref="#struct-1004777"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">175143</idno>
                <idno type="issn">2666-3643</idno>
                <idno type="eissn">2666-3643</idno>
                <title level="j">JTO Clinical and Research Reports</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">1</biblScope>
                  <biblScope unit="issue">3</biblScope>
                  <biblScope unit="pp">100052</biblScope>
                  <date type="datePub">2020-09</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.jtocrr.2020.100052</idno>
              <idno type="pubmed">34589947</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Prognosis</term>
                <term xml:lang="en">NSCLC</term>
                <term xml:lang="en">Non-small cell lung cancer</term>
                <term xml:lang="en">KRAS mutation</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.can">Life Sciences [q-bio]/Cancer</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Introduction - Methods - In the Biomarkers France study, 4894  mutations (26.2%) were detected in 4634 patients from the 17,664 enrolled patients with NSCLC. Survival and treatment data on noncurative stage III to IV NSCLC were available for 901 patients. First- and second-line treatment effects on progression-free survival and overall survival were analyzed according to the  mutations subtype.  Results - Over 95% of patients with  mutation were smokers or former smokers who were white (99.5%), presenting with adenocarcinoma (82.5%). The most common  mutation subtype was G12C (374 patients; 41.5%), followed by G12V (168; 18.6%), G12D (131; 14.5%), G12A (62; 6.9%), G13C (45; 5.0%), G13D (31; 3.4%), and others (10; 1%). Approximately 21% of patients had transition mutation and 68.2% had a transversion mutation. G12D and transition mutations were predominant in never-smokers. The median overall survival for patients with -mutated NSCLC was 8.1 months (95% confidence interval [CI]: 7.5-9.5), without any differences according to the different  subtypes mutations. The median progression-free survival was 4.6 months (95% CI: 4.2-5.1) for first-line treatment and 4.8 months (95% CI: 4.3-6.8) for second-line treatment, without any differences according to the different  subtypes mutations.  Conclusions -</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="department" xml:id="struct-542158" status="VALID">
          <idno type="RNSR">201923715Z</idno>
          <orgName>Groupe de recherche clinique Biomarqueurs Théranostiques des Cancers Bronchiques Non à Petites Cellules</orgName>
          <orgName type="acronym">GRC 4 - Theranoscan</orgName>
          <date type="start">2011-01-01</date>
          <desc>
            <address>
              <addrLine>Hôpital TenonService de PneumologieSecteur jaune, porte 12Bâtiment Lavoisier, 1er étage droite4 rue de la Chine75020 PARIS</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://sante.sorbonne-universite.fr/structures-de-recherche/grc-4-theranoscan</ref>
          </desc>
          <listRelation>
            <relation name="GRC4" active="#struct-413221" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-328304" status="VALID">
          <orgName>CHU Tenon [AP-HP]</orgName>
          <desc>
            <address>
              <addrLine>4 Rue de la Chine, 75020 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.aphp.fr/contenu/hopital-tenon-1</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-413221" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-211628" status="VALID">
          <idno type="IdRef">030378842</idno>
          <idno type="ROR">https://ror.org/04bckew43</idno>
          <orgName>Hôpitaux Universitaires de Strasbourg</orgName>
          <orgName type="acronym">HUS</orgName>
          <desc>
            <address>
              <addrLine>1 place de l'hôpital BP 426 67091 Strasbourg cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chru-strasbourg.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-528129" status="OLD">
          <idno type="IdRef">176976175</idno>
          <idno type="RNSR">201320589C</idno>
          <idno type="Wikidata">Q51784283</idno>
          <orgName>Interface de Recherche Fondamentale et Appliquée en Cancérologie</orgName>
          <orgName type="acronym">IRFAC - Inserm U1113</orgName>
          <date type="end">2023-12-31</date>
          <desc>
            <address>
              <addrLine>3 Avenue Molière – 67200 Strasbourg.</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-31840" type="direct"/>
            <relation active="#struct-502406" type="indirect"/>
            <relation active="#struct-199013" type="direct"/>
            <relation name="UMRS1113" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-543256" status="VALID">
          <idno type="IdRef">230325440</idno>
          <idno type="RNSR">201822694U</idno>
          <idno type="ROR">https://ror.org/0032jvj22</idno>
          <orgName>Nanomédecine Régénérative</orgName>
          <orgName type="acronym">NanoRegMed</orgName>
          <desc>
            <address>
              <addrLine>11 Rue HumannStrasbourg - France</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UMRS1260" active="#struct-199013" type="direct"/>
            <relation name="UMRS1260" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-574507" status="INCOMING">
          <orgName>Groupe hospitalier de la région de Mulhouse Sud-Alsace</orgName>
          <orgName type="acronym">GHRMSA</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-527029" status="VALID">
          <idno type="RNSR">201220266F</idno>
          <idno type="ROR">00w2q5j98</idno>
          <orgName>Institut de neurophysiopathologie</orgName>
          <orgName type="acronym">INP</orgName>
          <date type="start">2018-01-01</date>
          <desc>
            <address>
              <addrLine>Faculté de Médecine Campus Timone 27 Boulevard Jean MOULIN 13385 Marseille - France</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UMR7051" active="#struct-198056" type="direct"/>
            <relation name="UMR7051" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="department" xml:id="struct-484894" status="VALID">
          <orgName>Laboratoire de Transfert d'Oncologie Biologique [Hôpital Nord - APHM]</orgName>
          <desc>
            <address>
              <addrLine>Marseille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/site/plateformemoleculairecancer/laboratoires/service-de-transfert-d-oncologie-biologique</ref>
          </desc>
          <listRelation>
            <relation active="#struct-198056" type="direct"/>
            <relation active="#struct-300073" type="direct"/>
            <relation active="#struct-301315" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300165" status="VALID">
          <orgName>Centre Hospitalier Régional Universitaire de Besançon</orgName>
          <orgName type="acronym">CHRU Besançon</orgName>
          <desc>
            <address>
              <addrLine>3, boulevard A. Fleming - 25030 Besançon Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-besancon.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-182215" status="VALID">
          <idno type="IdRef">166218421</idno>
          <orgName>Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098)</orgName>
          <orgName type="acronym">RIGHT</orgName>
          <desc>
            <address>
              <addrLine>I.B.C.T. Bâtiment Inserm 240 Route de Dole/Rue F. Dolto 25000 Besançon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-fcomte.fr/pages/fr/menu1/recherche/la-recherche-a-l-ufc/umr-1098---relation-hote-greffon-18229-8143.html</ref>
          </desc>
          <listRelation>
            <relation name="UMR INSERM 1098" active="#struct-303623" type="direct"/>
            <relation active="#struct-439502" type="direct"/>
            <relation active="#struct-199980" type="indirect"/>
            <relation active="#struct-458810" type="direct"/>
            <relation active="#struct-426438" type="indirect"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-450027" status="OLD">
          <idno type="ROR">https://ror.org/014hxhm89</idno>
          <orgName>Institut Universitaire du Cancer de Toulouse - Oncopole</orgName>
          <orgName type="acronym">IUCT Oncopole - UMR 1037</orgName>
          <desc>
            <address>
              <addrLine>Av. Irène Joliot-Curie 31100 Toulouse</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-217752" type="direct"/>
            <relation active="#struct-443875" type="indirect"/>
            <relation active="#struct-300075" type="direct"/>
            <relation active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-208500" status="VALID">
          <orgName>Service Pneumologie-Allergologie [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Hôpital Larrey, 24, chemin de Pouvourville - TSA 30030 - 31059 Toulouse cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-toulouse.fr/-pneumologie-et-allergologie-</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1152912" type="direct"/>
            <relation active="#struct-300075" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-212722" status="VALID">
          <orgName>Groupement Hospitalier Lyon-Est</orgName>
          <orgName type="acronym">GHE</orgName>
          <desc>
            <address>
              <addrLine>59 Boulevard Pinel 69677 Bron</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-433319" status="VALID">
          <idno type="ROR">https://ror.org/04n1nkp35</idno>
          <orgName>Centre Hospitalier Intercommunal de Créteil</orgName>
          <orgName type="acronym">CHIC</orgName>
          <desc>
            <address>
              <addrLine>40 Avenue de Verdun 94000 Créteil</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chicreteil.fr</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-534830" status="VALID">
          <orgName>Institut de Biochimie et Biologie Moléculaire [CHRU Lille]</orgName>
          <desc>
            <address>
              <addrLine>Pôle Biologie Pathologie Génétique du Centre de Biologie Pathologie Pierre-Marie Degand -- Bd du Professeur J. Leclercq, 59 037 LILLE CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://biologiepathologie.chu-lille.fr/institutbiochimie/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-174729" type="direct"/>
            <relation active="#struct-425779" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1090097" status="VALID">
          <idno type="IdRef">192863495</idno>
          <idno type="RNSR">201521288D</idno>
          <idno type="ROR">https://ror.org/00bf6bf92</idno>
          <orgName>Oncogenesis, Stress, Signaling</orgName>
          <orgName type="acronym">OSS</orgName>
          <date type="start">2022-03-23</date>
          <desc>
            <address>
              <addrLine>Université de Rennes1 - CLCC Eugène Marquis, Rue de la Bataille Flandres Dunkerque, Bat D, 35042 Rennes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://oss-clcc-rennes.com/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-105160" type="direct"/>
            <relation active="#struct-301510" type="direct"/>
            <relation active="#struct-502406" type="indirect"/>
            <relation name="u1242" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301327" status="VALID">
          <idno type="ROR">https://ror.org/05qec5a53</idno>
          <orgName>Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]</orgName>
          <desc>
            <address>
              <addrLine>2 Rue Henri le Guilloux, 35000 Rennes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-259761" status="VALID">
          <idno type="IdRef">175206562</idno>
          <idno type="ROR">https://ror.org/057qpr032</idno>
          <orgName>Université de Bordeaux</orgName>
          <orgName type="acronym">UB</orgName>
          <desc>
            <address>
              <addrLine>35, place Pey Berland - 33076 Bordeaux</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-bordeaux.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300144" status="VALID">
          <idno type="IdRef">026606836</idno>
          <idno type="ISNI">0000000406394151</idno>
          <idno type="ROR">https://ror.org/02tcf7a68</idno>
          <orgName>CHU Clermont-Ferrand</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-552263" status="INCOMING">
          <orgName>INSERM UMR S1193</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300924" status="VALID">
          <idno type="ROR">https://ror.org/0377z4z10</idno>
          <orgName>Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand</orgName>
          <orgName type="acronym">CHU Dijon</orgName>
          <desc>
            <address>
              <addrLine>14 rue Paul Gaffarel - 21079 Dijon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-dijon.fr/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-123026" status="VALID">
          <idno type="ISNI">0000 0004 0639 1794</idno>
          <idno type="ROR">https://ror.org/05hmfw828</idno>
          <orgName>Centre de Lutte contre le Cancer Antoine Lacassagne [Nice]</orgName>
          <orgName type="acronym">UNICANCER/CAL</orgName>
          <date type="start">1961-01-01</date>
          <desc>
            <address>
              <addrLine>33, avenue de Valombrose, 06189 Nice</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.centreantoinelacassagne.org/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-502406" type="direct"/>
            <relation active="#struct-1039632" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-81952" status="VALID">
          <orgName>Intergroupe Francophone de Cancérologie Thoracique [Paris]</orgName>
          <orgName type="acronym">IFCT</orgName>
          <desc>
            <address>
              <addrLine>10 rue de la Grange Batelière 75009 PARIS</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ifct.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-205255" status="VALID">
          <orgName>Service de pneumologie [Centre Hospitalier Lyon Sud - HCL]</orgName>
          <desc>
            <address>
              <addrLine>Chemin du Grand Revoyet 69495 Pierre-Bénite</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/web/1846</ref>
          </desc>
          <listRelation>
            <relation active="#struct-353860" type="direct"/>
            <relation active="#struct-300074" type="indirect"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-536855" status="VALID">
          <orgName>Service d'oncologie multidisciplinaire innovations thérapeutiques [Hôpital Nord - APHM]</orgName>
          <desc>
            <address>
              <addrLine>Hôpital NordPavillon Mistral6ème étage A</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/service/oncologie-multidisciplinaire-innovations-therapeutiques-hopital-nord</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300073" type="direct"/>
            <relation active="#struct-301315" type="direct"/>
          </listRelation>
        </org>
        <org type="department" xml:id="struct-18189" status="VALID">
          <orgName>Service de pneumologie [CHU Cochin]</orgName>
          <desc>
            <address>
              <addrLine>27 rue du Faubourg Saint-Jacques 75014 Paris</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300123" type="direct"/>
            <relation active="#struct-300068" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1004777" status="VALID">
          <idno type="IdRef">158039203</idno>
          <idno type="ISNI">0000 0004 0620 5824 </idno>
          <idno type="RNSR">200716512X</idno>
          <orgName>Centre de Recherche des Cordeliers</orgName>
          <orgName type="acronym">CRC (UMR_S_1138 / U1138)</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>15 rue de l'Ecole de Médecine - Bâtiment B - 75270 Paris Cedex 06</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.crc.jussieu.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-110691" type="direct"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation name="U1138" active="#struct-303623" type="direct"/>
            <relation active="#struct-413221" type="direct"/>
            <relation name="UMR_S_1138" active="#struct-557826" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-413221" status="VALID">
          <idno type="IdRef">221333754</idno>
          <idno type="ROR">https://ror.org/02en5vm52</idno>
          <orgName>Sorbonne Université</orgName>
          <orgName type="acronym">SU</orgName>
          <date type="start">2018-01-01</date>
          <desc>
            <address>
              <addrLine>21 rue de l’École de médecine - 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-universite.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300068" status="VALID">
          <idno type="ROR">https://ror.org/00pg5jh14</idno>
          <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
          <orgName type="acronym">AP-HP</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-31840" status="VALID">
          <orgName>Centre Paul Strauss</orgName>
          <orgName type="acronym">CRLCC Paul Strauss</orgName>
          <desc>
            <address>
              <addrLine>17 rue Albert Calmette BP 23025 67033 Strasbourg</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.centre-paul-strauss.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-502406" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-502406" status="VALID">
          <orgName>UNICANCER</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75654 Paris Cedex 13</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicancer.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-199013" status="VALID">
          <idno type="IdRef">131056549</idno>
          <idno type="ROR">https://ror.org/00pg6eq24</idno>
          <orgName>Université de Strasbourg</orgName>
          <orgName type="acronym">UNISTRA</orgName>
          <desc>
            <address>
              <addrLine>4 rue Blaise Pascal - CS 90032 - 67081 Strasbourg cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.unistra.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-198056" status="VALID">
          <idno type="IdRef">15863621X</idno>
          <idno type="ISNI">0000 0001 2176 4817</idno>
          <idno type="ROR">https://ror.org/035xkbk20</idno>
          <orgName>Aix Marseille Université</orgName>
          <orgName type="acronym">AMU</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-amu.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300073" status="VALID">
          <idno type="ROR">https://ror.org/002cp4060</idno>
          <orgName>Assistance Publique - Hôpitaux de Marseille</orgName>
          <orgName type="acronym">APHM</orgName>
          <desc>
            <address>
              <addrLine>Direction générale AP-HM80, rue Brochier13 354 Marseille Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301315" status="VALID">
          <idno type="ISNI">0000 0001 0304 0719 </idno>
          <idno type="ROR">https://ror.org/029a4pp87</idno>
          <orgName>Hôpital Nord [CHU - APHM]</orgName>
          <date type="start">1964</date>
          <desc>
            <address>
              <addrLine>Hôpital Nord - Chemin des Bourrely13915Marseille cedex 20</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/nos-hopitaux/hopital-nord</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-439502" status="VALID">
          <idno type="ROR">https://ror.org/02k9vew78</idno>
          <orgName>Établissement Français du Sang Bourgogne-Franche-Comté [Besançon]</orgName>
          <orgName type="acronym">EFS BFC - Besançon</orgName>
          <desc>
            <address>
              <addrLine>1 Boulevard Fleming 25020 Besançon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.efs.sante.fr/lefs-en-bourgogne-franche-comte</ref>
          </desc>
          <listRelation>
            <relation active="#struct-199980" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-199980" status="VALID">
          <orgName>Établissement Français du Sang [La Plaine Saint-Denis]</orgName>
          <orgName type="acronym">EFS</orgName>
          <date type="start">2000-01-01</date>
          <desc>
            <address>
              <addrLine>20 Avenue du Stade de France 93218 La Plaine Saint Denis</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.dondusang.net</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-458810" status="VALID">
          <idno type="IdRef">026403188</idno>
          <idno type="ISNI">0000000121883779</idno>
          <idno type="ROR">https://ror.org/03pcc9z86</idno>
          <orgName>Université Marie et Louis Pasteur</orgName>
          <orgName type="acronym">UMLP</orgName>
          <desc>
            <address>
              <addrLine>1 rue Goudimel25030 Besançon cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.umlp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-426438" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-426438" status="VALID">
          <idno type="IdRef">200716271</idno>
          <idno type="ISNI">0000 0004 4910 6615</idno>
          <idno type="ROR">https://ror.org/02dn7x778</idno>
          <orgName>Université Bourgogne Franche-Comté [COMUE]</orgName>
          <orgName type="acronym">UBFC</orgName>
          <date type="start">2015-04-01</date>
          <date type="end">2024-12-31</date>
          <desc>
            <address>
              <addrLine>32, avenue de l’observatoire25000 BESANCON</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ubfc.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-217752" status="OLD">
          <idno type="IdRef">026404672</idno>
          <idno type="ISNI">0000000121617331</idno>
          <idno type="ROR">https://ror.org/02v6kpv12</idno>
          <idno type="Wikidata">Q1273188</idno>
          <orgName>Université Toulouse III - Paul Sabatier</orgName>
          <orgName type="acronym">UT3</orgName>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>118 route de Narbonne - 31062 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-tlse3.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-443875" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-443875" status="VALID">
          <idno type="ROR">https://ror.org/017tgbk05</idno>
          <orgName>Communauté d'universités et établissements de Toulouse</orgName>
          <orgName type="acronym">Comue de Toulouse</orgName>
          <desc>
            <address>
              <addrLine>41 Allée Jules Guesde, 31000 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-toulouse.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300075" status="VALID">
          <orgName>Centre Hospitalier Universitaire de Toulouse</orgName>
          <orgName type="acronym">CHU Toulouse</orgName>
          <desc>
            <address>
              <addrLine>regroupe les hôpitaux  Purpan, Rangueil, Pierre-Paul Riquet, Larey, Paule de Viguier, Hôtel Dieu Saint-Jacques, La Grave, etc.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-toulouse.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1152912" status="VALID">
          <orgName>Pôle Clinique des Voies respiratoires [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Toulouse</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300075" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-174729" status="VALID">
          <orgName>Pôle de Biologie Pathologie Génétique [CHU Lille]</orgName>
          <desc>
            <address>
              <addrLine>Centre de Biologie Pathologie Pierre-Marie Degand - Bd du Professeur J. Leclercq 59 037 LILLE CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://biologiepathologie.chu-lille.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-425779" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-425779" status="VALID">
          <idno type="IdRef">034424636</idno>
          <idno type="ISNI">0000000404718845</idno>
          <idno type="ROR">https://ror.org/02ppyfa04</idno>
          <idno type="Wikidata">Q2945741</idno>
          <orgName>Centre Hospitalier Régional Universitaire [CHU Lille]</orgName>
          <orgName type="acronym">CHRU Lille</orgName>
          <desc>
            <address>
              <addrLine>CHU/CHRU Lille - 2, avenue Oscar Lambret - 59037 Lille Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chru-lille.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-105160" status="VALID">
          <idno type="IdRef">26693823X</idno>
          <idno type="ROR">https://ror.org/015m7wh34</idno>
          <orgName>Université de Rennes</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>
            <address>
              <addrLine>Campus de Beaulieu, 263 avenue Général Leclerc, CS 74205, 35042 RENNES CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301510" status="VALID">
          <idno type="ROR">https://ror.org/01yezas83</idno>
          <orgName>CRLCC Eugène Marquis</orgName>
          <orgName type="acronym">CRLCC</orgName>
          <desc>
            <address>
              <addrLine>Avenue Bataille Flandres-Dunkerque 35042 RENNES CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.centre-eugene-marquis.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-502406" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-1039632" status="VALID">
          <idno type="IdRef">241035694</idno>
          <idno type="ROR">https://ror.org/019tgvf94</idno>
          <orgName>Université Côte d'Azur</orgName>
          <orgName type="acronym">UniCA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Parc Valrose, 28, avenue Valrose 06108 Nice Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://univ-cotedazur.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-353860" status="VALID">
          <idno type="ROR">https://ror.org/023xgd207</idno>
          <orgName>Centre Hospitalier Lyon Sud [CHU - HCL]</orgName>
          <orgName type="acronym">CHLS</orgName>
          <desc>
            <address>
              <addrLine>165 Chemin du Grand Revoyet69495 Pierre-Bénite</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/centre-hospitalier-lyon-sud</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300123" status="VALID">
          <idno type="IdRef">030428653</idno>
          <idno type="ROR">https://ror.org/00ph8tk69</idno>
          <orgName>Hôpital Cochin [AP-HP]</orgName>
          <desc>
            <address>
              <addrLine>27 Rue du Faubourg Saint-Jacques 75014 Paris</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-110691" status="VALID">
          <idno type="IdRef">026375478</idno>
          <idno type="ISNI">0000000121955365</idno>
          <idno type="ROR">https://ror.org/046b3cj80</idno>
          <orgName>École Pratique des Hautes Études</orgName>
          <orgName type="acronym">EPHE</orgName>
          <date type="start">1868-01-01</date>
          <desc>
            <address>
              <addrLine>4-14 Rue Ferrus, 75014 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ephe.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-564132" status="VALID">
          <idno type="IdRef">241597595</idno>
          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-557826" status="VALID">
          <idno type="IdRef">236453505</idno>
          <idno type="ISNI">0000 0004 7885 7602</idno>
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris Cité</orgName>
          <orgName type="acronym">UPCité</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>85 boulevard Saint-Germain75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://u-paris.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>