X-ray computed tomography (XCT) is a well known method for three-dimensional characterization of materials that is established as a powerful tool in high-pressure/high-temperature research. The optimization of synchrotron beamlines and the development of fast high-efficiency detectors now allow the addition of a temporal dimension to tomography studies under extreme conditions. Presented here is the experimental setup developed on the PSICHE beamline at SOLEIL to perform high-speed XCT in the Ultra-fast Tomography Paris–Edinburgh cell (UToPEc). The UToPEc is a compact panoramic (165° angular aperture) press optimized for fast tomography that can access 10 GPa and 1700°C. It is installed on a high-speed rotation stage (up to 360° s −1 ) and allows the acquisition of a full computed tomography (CT) image with micrometre spatial resolution within a second. This marks a major technical breakthrough for time-lapse XCT and the real-time visualization of evolving dynamic systems. In this paper, a practical step-by-step guide to the use of the technique is provided, from the collection of CT images and their reconstruction to performing quantitative analysis, while accounting for the constraints imposed by high-pressure and high-temperature experimentation. The tomographic series allows the tracking of key topological parameters such as phase fractions from 3D volumetric data, and also the evolution of morphological properties ( e.g. volume, flatness, dip) of each selected entity. The potential of this 4D tomography is illustrated by percolation experiments of carbonate melts within solid silicates, relevant for magma transfers in the Earth's mantle.