Laser synthesis: a solvent-free approach for the preparation of phenylthiazolo[5,4-b]pyridine derivatives
Résumé
We describe here a rapid and straightforward solvent-free method to access phenylthiazolo[5,4-b]pyridines using a Nd-YAG laser NANO-NY81-10 (l ¼ 355 nm, 10 Hz pulse frequency; 8 ns pulse duration). This newly presented method successfully brings several improvements to the laser assisted synthesis of N,Sheterocycles. We are able to provide a solvent-, metal-and base-free method with good yield and a substantial reduction in reaction time.
Domaines
Chimie organique| Origine | Fichiers éditeurs autorisés sur une archive ouverte |
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