Universal force correlations in an RNA-DNA unzipping experiment
Résumé
We study unzipping of a complementary RNA-DNA helix applied to an external force, focusing on the force-force correlations. While at the microscopic level these are given by the sequence, the experiment measures effective, macroscopic correlations. The latter are sequence independent, i.e., universal, and constitute the central object of the underlying field theory of disordered systems. Comparing field-theory predictions and the exact solution of a one-dimensional toy model with the experiment, we find an excellent agreement, confirming fundamental theoretical concepts via biologically inspired experiments.
Mots clés
- Irreversible processes
- Thermodynamics
- Self-organized criticality
- Polymer synthesis
- Polymer conformation & topology
- Polymer behavior
- Optimization problems
- Nonequilibrium statistical mechanics
- Nonequilibrium and irreversible thermodynamics
- Mathematical physics
- Elastic forces
- Elastic deformation
- Critical phenomena
- Complex systems
- Classical statistical mechanics
- Chirality
- Biomolecular self-assembly
- Biomolecular interactions
Domaines
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