Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France, June to July 2021 - Archive ouverte HAL Access content directly
Journal Articles Eurosurveillance Year : 2021

Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France, June to July 2021

Abstract

We compared PCR results from SARS-CoV-2-positive patients tested in the community in France from 14 June to 30 July 2021. In asymptomatic individuals, Cq values were significantly higher in fully vaccinated than non-fully vaccinated individuals (effect size: 1.7; 95% CI: 1–2.3; p < 10 −6 ). In symptomatic individuals and controlling for time since symptoms, the difference vanished (p = 0.26). Infections with the Delta variant had lower Cq values at symptom onset than with Alpha (effect size: −3.32; 95% CI: −4.38 to −2.25; p < 10 −6 ).
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Dates and versions

hal-03370775 , version 1 (08-10-2021)

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François Blanquart, Clémence Abad, Joëvin Ambroise, Mathieu Bernard, Gina Cosentino, et al.. Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France, June to July 2021. Eurosurveillance, 2021, 26 (37), pp.2100824. ⟨10.2807/1560-7917.ES.2021.26.37.2100824⟩. ⟨hal-03370775⟩
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