SARS-CoV-2 variants of concern are associated with lower RT-PCR amplification cycles between January and March 2021 in France - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue International Journal of Infectious Diseases Année : 2021

SARS-CoV-2 variants of concern are associated with lower RT-PCR amplification cycles between January and March 2021 in France

Résumé

SARS-CoV-2 variants raise concern regarding the mortality caused by COVID-19 epidemics. We analyse 88,375 cycle amplication (Ct) values from variant-specic RT-PCR tests performed between January 26 and March 13, 2021. We estimate that on March 12, nearly 85% of the infections were caused by the Alpha variant and that its transmission advantage over wild type strains was between 38 and 44%. We also nd that tests positive for Alpha and Beta/Gamma variants exhibit signicantly lower cycle threshold (Ct) values.
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Dates et versions

hal-03366559 , version 1 (06-10-2021)

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Benedicte Roquebert, Stéphanie Haim-Boukobza, Sabine Trombert-Paolantoni, Emmanuel Lecorche, Laura Verdurme, et al.. SARS-CoV-2 variants of concern are associated with lower RT-PCR amplification cycles between January and March 2021 in France. International Journal of Infectious Diseases, 2021, ⟨10.1016/j.ijid.2021.09.076⟩. ⟨hal-03366559⟩
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