The plastic behavior of fcc materials is studied under complex loading path at room temperature. Multi-scale experimental results are compared to finite element computations of polycrystalline aggregates, and to simulation by homogenization techniques. Simple loading path combinations are considered for different sample orientations. Local strain field measurements are obtained by digital correlation of scanning electron microscope images, whereas global strains are measured by classical extensometry. A polycrystalline aggregate taking into account the material microstructure is used to perform finite element simulations corresponding to the experiments. The texture measured by X-ray diffraction is represented. Several single crystal models, using the 12 slip systems of the octahedral families, are introduced. Various assumptions are considered for the description of the self and latent hardening. The comparisons between the simulation and the experiments are made on three types of variables : on a global level, with the description of the macroscopic stress-strain curve, on a local level, by considering the local fields, and in terms of phase averages. Informations about the consistency of the transition rules are deduced.