Distribution of the species of the Anopheles gambiae complex and first evidence of Anopheles merus as a malaria vector in Madagascar - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Malaria Journal Année : 2003

Distribution of the species of the Anopheles gambiae complex and first evidence of Anopheles merus as a malaria vector in Madagascar

Résumé

Background: Members of the Anopheles gambiae complex are amongst the best malaria vectors in the world, but their vectorial capacities vary between species and populations. A large-scale sampling of An. gambiae sensu lato was carried out in various bioclimatic domains of Madagascar. Local abundance of an unexpected member of this complex raised questions regarding its role in malaria transmission. Methods: Sampling took place at 38 sites and 2,067 females were collected. Species assessment was performed using a PCR targeting a sequence in the IGS of the rDNA. Analysis focused on the relative prevalence of the species per site, bioclimatic domain and altitude. Infectivity of Anopheles merus was assessed using an ELISA to detect the presence of malarial circumsporozoite protein in the head-thorax. Results: Three species were identified: An. gambiae, Anopheles arabiensis and An. merus. The distribution of each species is mainly a function of bioclimatic domains and, to a lesser extent, altitude. An. arabiensis is present in all bioclimatic domains with highest prevalence in sub-humid, dry and sub-arid domains. An. gambiae has its highest prevalence in the humid domain, is in the minority in dry areas, rare in sub-humid and absent in sub-arid domains. An. merus is restricted to the coastal fringe in the south and west; it was in the majority in one southern village. The majority of sites were sympatric for at least two of the species (21/38) and two sites harboured all three species. The role of An. merus as malaria vector was confirmed in the case of two human-biting females, which were ELISA-positive for Plasmodium falciparum. Conclusion: Despite the huge environmental (mainly man-made) changes in Madagascar, the distribution of An. gambiae and An. arabiensis appears unchanged for the past 35 years. The
Fichier principal
Vignette du fichier
2003-3_Leong Pock Tsy et al.-Distribution gambiae Mada_Malaria Journal 2.pdf (286.51 Ko) Télécharger le fichier
Origine : Publication financée par une institution

Dates et versions

hal-03359413 , version 1 (30-09-2021)

Identifiants

Citer

Jean-Michel Pock Tsy, Jean-Bernard Duchemin, Laurence Marrama, Patrick Rabarison, Gilbert Le Goff, et al.. Distribution of the species of the Anopheles gambiae complex and first evidence of Anopheles merus as a malaria vector in Madagascar. Malaria Journal, 2003, 2 (1), pp.33. ⟨10.1186/1475-2875-2-33⟩. ⟨hal-03359413⟩
15 Consultations
30 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More