Functionnectome as a framework to analyse the contribution of brain circuits to fMRI. - Archive ouverte HAL
Article Dans Une Revue Communications Biology Année : 2021

Functionnectome as a framework to analyse the contribution of brain circuits to fMRI.

Résumé

In recent years, the field of functional neuroimaging has moved away from a pure localisationist approach of isolated functional brain regions to a more integrated view of these regions within functional networks. However, the methods used to investigate functional networks rely on local signals in grey matter and are limited in identifying anatomical circuitries supporting the interaction between brain regions. Mapping the brain circuits mediating the functional signal between brain regions would propel our understanding of the brain's functional signatures and dysfunctions. We developed a method to unravel the relationship between brain circuits and functions: The Functionnectome. The Functionnectome combines the functional signal from fMRI with white matter circuits' anatomy to unlock and chart the first maps of functional white matter. To showcase this method's versatility, we provide the first functional white matter maps revealing the joint contribution of connected areas to motor, working memory, and language functions. The Functionnectome comes with an open-source companion software and opens new avenues into studying functional networks by applying the method to already existing datasets and beyond task fMRI.
Fichier principal
Vignette du fichier
13014_Nozais-CommBiol_inpress_21.pdf (1.98 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03346646 , version 1 (16-09-2021)

Identifiants

Citer

Victor Nozais, Stephanie J Forkel, Chris Foulon, Laurent Petit, Michel Thiebaut de Schotten. Functionnectome as a framework to analyse the contribution of brain circuits to fMRI.. Communications Biology, 2021, ⟨10.1038/s42003-021-02530-2⟩. ⟨hal-03346646⟩
15 Consultations
39 Téléchargements

Altmetric

Partager

More