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Conference Papers Year : 2021

Blood Glucose Regulation in Patients with Type 1 Diabetes Mellitus: A Robust MRAC Approach

Abstract

This paper deals with the problem of robust blood glucose regulation in critically ill patients affected by type 1 diabetes mellitus. The blood glucose measurement and insulin infusion are intravenous. The proposed algorithm regulates blood glucose and keeps it in the normoglycemia range, i.e., 70–180 mg/dl. To this aim, a control law is proposed based on a Nonlinear Model Reference Adaptive Control approach. The algorithm is composed of nonlinear adaptive gains that ensure convergence to zero of the regulation error. The approach is validated in the UVA/Padova metabolic simulator for ten in silico adult patients with unannounced meals.
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Dates and versions

hal-03328014 , version 1 (27-08-2021)

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  • HAL Id : hal-03328014 , version 1

Cite

Roberto Franco, Héctor Ríos, Alejandra Ferreira de Loza, Denis Efimov, Louis Cassany, et al.. Blood Glucose Regulation in Patients with Type 1 Diabetes Mellitus: A Robust MRAC Approach. 60th IEEE Conference on Decision and Control, Dec 2021, Austin, United States. ⟨hal-03328014⟩
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