Synthesis of 2-phosphonoheterocycles via base-promoted 5-endo cyclization
Résumé
Herein, a synthesis of 2-phosphonodihydrofurans and 2-phosphonodihydropyrroles via 5-endo cyclization of O-and N-propargylated compounds is described. The reaction is promoted by potassium tert-butoxide and allows a fast access to interesting heterocycles which were easily converted into 2-arylated pyrroles under acidic conditions.
Domaines
ChimieOrigine | Fichiers produits par l'(les) auteur(s) |
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