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                <term xml:lang="en">Asclepias syriaca L.</term>
                <term xml:lang="en">milkweed</term>
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              <p>This study aims to evaluate the potential of milkweed as potential candidate to constructbiodegradable scaffold for bone regeneration. A mat made of milkweed, polyethylene, andpolypropylene was treated with an atmospheric pressure plasma to functionalize the surface of thepolymer assembly with carboxylic acid groups, which enable to conjugate bioactive molecules, whileaccelerating the degradation of milkweed. Degradation tests demonstrated substantial decrease ofthe weight of the treated polymer mat as compared to untreated one. Biological assays revealed thatthe polymer assembly promoted preosteoblast MC3T3 cells recruitment with a significantenhancement observed on the RGD-grafted polymer mat.</p>
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