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Communication Dans Un Congrès Année : 2020

Resolution, visibility and contrast enhancement in 2D and 3D photoacoustic imaging: a unified approach based on absorption fluctuations analysis

Résumé

Photoacoustic imaging provides optical contrast at depth beyond the optical transport mean free path. From the generation of ultrasound by light absorption, images can be reconstructed at the acoustic resolution (~100 μm) with a penetration of a few cm. Improving the resolution to bring it closer to the cellular scale is a major challenge. Moreover, the design of imaging systems often leads to limited view artifacts, where a part of the information needed for a complete reconstruction of the objects is missing. We studied multiple approaches for improving the resolution, visibility and contrast of photoacoustic imaging. We will show that a dynamic approach based on the analysis of fluctuations induced by a flow of absorbers can significantly improve resolution. The fluctuation approach, which has the advantage to use the native contrast of blood, also solves the visibility problem in 2D imaging of flow phantoms using a linear transducer (128 elements, 15 MHz). We will show this approach is effective using a sparse array of detectors for 3D imaging. Using a sparse spherical array (256 elements, 8 MHz), 3D imaging experiments in the chicken embryo vasculature model evidenced the presence of clutter around the reconstructed objects due to the low number of channels, resulting in a poor contrast. This clutter was greatly reduced by the fluctuation approach. We will further discuss photoacoustic fluctuations and ultrasound power Doppler similarities. Thus, photoacoustic fluctuation imaging overcomes many limitations of conventional imaging and will be further evaluated for in-vivo imaging.
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Dates et versions

hal-03235365 , version 1 (27-05-2021)

Identifiants

Citer

Bastien Arnal, Guillaum Godefroy, Sergey Vilov, Emmanuel Bossy. Resolution, visibility and contrast enhancement in 2D and 3D photoacoustic imaging: a unified approach based on absorption fluctuations analysis. Forum Acusticum, Dec 2020, Lyon, France. pp.1787-1790, ⟨10.48465/fa.2020.1127⟩. ⟨hal-03235365⟩
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