Crossing a fitness valley as a metastable transition in a stochastic population model - Archive ouverte HAL
Article Dans Une Revue The Annals of Applied Probability Année : 2019

Crossing a fitness valley as a metastable transition in a stochastic population model

Résumé

We consider a stochastic model of population dynamics where each individual is characterised by a trait in {0,1,…,L} and has a natural reproduction rate, a logistic death rate due to age or competition and a probability of mutation towards neighbouring traits at each reproduction event. We choose parameters such that the induced fitness landscape exhibits a valley: mutant individuals with negative fitness have to be created in order for the population to reach a trait with positive fitness. We focus on the limit of large population and rare mutations at several speeds. In particular, when the mutation rate is low enough, metastability occurs: the exit time of the valley is an exponentially distributed random variable.
Fichier principal
Vignette du fichier
2019_Bovier.pdf (427.72 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Licence

Dates et versions

hal-03230266 , version 1 (20-07-2023)

Licence

Identifiants

Citer

Anton Bovier, Loren Coquille, Charline Smadi. Crossing a fitness valley as a metastable transition in a stochastic population model. The Annals of Applied Probability, 2019, 29 (6), pp.541-3589. ⟨10.1214/19-AAP1487⟩. ⟨hal-03230266⟩
28 Consultations
17 Téléchargements

Altmetric

Partager

More