<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-03223991</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-19T02:22:35+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Large-scale screening of lipase acid deficiency in at risk population</title>
            <author role="aut">
              <persName>
                <forename type="first">Abdellah</forename>
                <surname>Tebani</surname>
              </persName>
              <email type="md5">84b524be981fbddac4a3813d565bba0a</email>
              <email type="domain">chu-rouen.fr</email>
              <idno type="idhal" notation="numeric">809950</idno>
              <idno type="halauthorid" notation="string">1152334-809950</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8901-2678</idno>
              <idno type="IDREF">https://www.idref.fr/22363526X</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-6868-2018</idno>
              <idno type="VIAF">https://viaf.org/viaf/193151836609520402600</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-6868-2018</idno>
              <affiliation ref="#struct-519394"/>
              <affiliation ref="#struct-300147"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bénédicte</forename>
                <surname>Sudrié-Arnaud</surname>
              </persName>
              <idno type="halauthorid">1689688-0</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Hela</forename>
                <surname>Boudabous</surname>
              </persName>
              <idno type="halauthorid">1422072-0</idno>
              <affiliation ref="#struct-207896"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anais</forename>
                <surname>Brassier</surname>
              </persName>
              <idno type="halauthorid">2156430-0</idno>
              <affiliation ref="#struct-414766"/>
              <affiliation ref="#struct-1004662"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Rodolphe</forename>
                <surname>Anty</surname>
              </persName>
              <idno type="idhal" notation="numeric">761750</idno>
              <idno type="halauthorid" notation="string">417242-761750</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8194-9805</idno>
              <affiliation ref="#struct-180122"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sarah</forename>
                <surname>Snanoudj</surname>
              </persName>
              <idno type="halauthorid">1637898-0</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Armand</forename>
                <surname>Abergel</surname>
              </persName>
              <email type="md5">0ff4d0c65bd4051ab42235966df2dfa7</email>
              <email type="domain">chu-clermontferrand.fr</email>
              <idno type="idhal" notation="numeric">763073</idno>
              <idno type="halauthorid" notation="string">489930-763073</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7480-1052</idno>
              <idno type="IDREF">https://www.idref.fr/109301269</idno>
              <idno type="VIAF">https://viaf.org/viaf/208228281</idno>
              <idno type="VIAF">https://viaf.org/viaf/306320681</idno>
              <idno type="ISNI">http://isni.org/isni/0000000139574915</idno>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie-Thérèse</forename>
                <surname>Abi Warde</surname>
              </persName>
              <idno type="halauthorid">1621423-0</idno>
              <affiliation ref="#struct-300149"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Edouard</forename>
                <surname>Bardou-Jacquet</surname>
              </persName>
              <idno type="halauthorid">523715-0</idno>
              <affiliation ref="#struct-480788"/>
              <affiliation ref="#struct-301327"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Reda</forename>
                <surname>Belbouab</surname>
              </persName>
              <idno type="halauthorid">1714355-0</idno>
              <affiliation ref="#struct-1192911"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Eloi</forename>
                <surname>Blanchet</surname>
              </persName>
              <idno type="halauthorid">2206356-0</idno>
              <affiliation ref="#struct-1077089"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Corinne</forename>
                <surname>Borderon</surname>
              </persName>
              <idno type="halauthorid">1234073-0</idno>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Pierre</forename>
                <surname>Bronowicki</surname>
              </persName>
              <email type="md5">221f64c47bc185c3f9bf43d9ed0a506b</email>
              <email type="domain">chu-nancy.fr</email>
              <idno type="idhal" notation="numeric">1213521</idno>
              <idno type="halauthorid" notation="string">355189-1213521</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-1631-500X</idno>
              <idno type="IDREF">https://www.idref.fr/077913604</idno>
              <affiliation ref="#struct-300157"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bertrand</forename>
                <surname>Cariou</surname>
              </persName>
              <email type="md5">1eed1f2b671cbc31cf91c6a2af157d87</email>
              <email type="domain">univ-nantes.fr</email>
              <idno type="idhal" notation="numeric">761594</idno>
              <idno type="halauthorid" notation="string">410249-761594</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1580-8040</idno>
              <idno type="IDREF">https://www.idref.fr/075934981</idno>
              <affiliation ref="#struct-474972"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Claire</forename>
                <surname>Carette</surname>
              </persName>
              <idno type="idhal" notation="numeric">776094</idno>
              <idno type="halauthorid" notation="string">975256-776094</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8175-0369</idno>
              <idno type="IDREF">https://www.idref.fr/087685159</idno>
              <affiliation ref="#struct-300119"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Myriam</forename>
                <surname>Dabbas</surname>
              </persName>
              <idno type="halauthorid">1876767-0</idno>
              <affiliation ref="#struct-414766"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Hélène</forename>
                <surname>Dranguet</surname>
              </persName>
              <idno type="halauthorid">1707536-0</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Victor</forename>
                <surname>de Ledinghen</surname>
              </persName>
              <idno type="idhal" notation="numeric">756883</idno>
              <idno type="halauthorid" notation="string">159892-756883</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6414-1951</idno>
              <affiliation ref="#struct-495627"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean</forename>
                <surname>Ferrières</surname>
              </persName>
              <email type="md5">9a93364fb6dcec474b47819b98eb0b17</email>
              <email type="domain">mail.cict.fr</email>
              <idno type="idhal" notation="numeric">1064118</idno>
              <idno type="halauthorid" notation="string">158571-1064118</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6144-1297</idno>
              <idno type="IDREF">https://www.idref.fr/061532940</idno>
              <affiliation ref="#struct-1160981"/>
              <affiliation ref="#struct-101902"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Maeva</forename>
                <surname>Guillaume</surname>
              </persName>
              <idno type="halauthorid">1237001-0</idno>
              <affiliation ref="#struct-300075"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michel</forename>
                <surname>Krempf</surname>
              </persName>
              <idno type="halauthorid">305750-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Florence</forename>
                <surname>Lacaille</surname>
              </persName>
              <idno type="idhal" notation="numeric">769724</idno>
              <idno type="halauthorid" notation="string">745209-769724</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5272-4970</idno>
              <affiliation ref="#struct-414766"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Dominique</forename>
                <surname>Larrey</surname>
              </persName>
              <email type="md5">5aad1f0c817f20f72c0bb128156047f2</email>
              <email type="domain">chu-montpellier.fr</email>
              <idno type="idhal" notation="numeric">759679</idno>
              <idno type="halauthorid" notation="string">308497-759679</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0892-3489</idno>
              <affiliation ref="#struct-443668"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Vincent</forename>
                <surname>Leroy</surname>
              </persName>
              <idno type="halauthorid">7566-0</idno>
              <affiliation ref="#struct-1043222"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marietta</forename>
                <surname>Musikas</surname>
              </persName>
              <idno type="halauthorid">2206357-0</idno>
              <affiliation ref="#struct-300185"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Eric</forename>
                <surname>Nguyen-Khac</surname>
              </persName>
              <email type="md5">96b5d383b0281131d1e737cbf077f291</email>
              <email type="domain">chu-amiens.fr</email>
              <idno type="idhal" notation="numeric">863504</idno>
              <idno type="halauthorid" notation="string">417581-863504</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8672-4146</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/FMD-8891-2022</idno>
              <idno type="IDREF">https://www.idref.fr/081127634</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/FMD-8891-2022</idno>
              <affiliation ref="#struct-580112"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Denis</forename>
                <surname>Ouzan</surname>
              </persName>
              <idno type="idhal" notation="numeric">769426</idno>
              <idno type="halauthorid" notation="string">737253-769426</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8035-2062</idno>
              <affiliation ref="#struct-469997"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Marc</forename>
                <surname>Perarnau</surname>
              </persName>
              <idno type="halauthorid">448119-0</idno>
              <affiliation ref="#struct-179009"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Carine</forename>
                <surname>Pilon</surname>
              </persName>
              <idno type="halauthorid">1685218-0</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Vlad</forename>
                <surname>Ratzlu</surname>
              </persName>
              <idno type="halauthorid">2206358-0</idno>
              <affiliation ref="#struct-541912"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alice</forename>
                <surname>Thebaut</surname>
              </persName>
              <idno type="halauthorid">2206359-0</idno>
              <affiliation ref="#struct-312432"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Thierry</forename>
                <surname>Thevenot</surname>
              </persName>
              <idno type="halauthorid">448181-0</idno>
              <affiliation ref="#struct-300165"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Isabelle</forename>
                <surname>Tragin</surname>
              </persName>
              <idno type="halauthorid">2206360-0</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Valérie</forename>
                <surname>Triolo</surname>
              </persName>
              <idno type="halauthorid">2206361-0</idno>
              <affiliation ref="#struct-107940"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bruno</forename>
                <surname>Verges</surname>
              </persName>
              <email type="md5">6e1db1a76ce1ba3e1d0fccd4423e6499</email>
              <email type="domain">chu-dijon.fr</email>
              <idno type="idhal" notation="string">bruno-verges</idno>
              <idno type="idhal" notation="numeric">13656</idno>
              <idno type="halauthorid" notation="string">4815-13656</idno>
              <idno type="IDREF">https://www.idref.fr/030858453</idno>
              <affiliation ref="#struct-489317"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sabrina</forename>
                <surname>Vergnaud</surname>
              </persName>
              <idno type="halauthorid">508499-0</idno>
              <affiliation ref="#struct-257328"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">Soumeya</forename>
                <surname>Bekri</surname>
              </persName>
              <email type="md5">5e5f3467a3d4af860fffddb6f4dd0ba3</email>
              <email type="domain">univ-rouen.fr</email>
              <idno type="idhal" notation="numeric">767750</idno>
              <idno type="halauthorid" notation="string">661326-767750</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6184-7270</idno>
              <idno type="IDREF">https://www.idref.fr/128937300</idno>
              <affiliation ref="#struct-519394"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Laurent</forename>
                <surname>Jonchère</surname>
              </persName>
              <email type="md5">dc1f1e9bdb3dc2065f8bf1bfd5663118</email>
              <email type="domain">univ-rennes.fr</email>
            </editor>
            <funder>This research was funded by Alexion Pharmaceuticals.</funder>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2021-06-11 14:55:56</date>
              <date type="whenModified">2026-04-02 15:54:04</date>
              <date type="whenReleased">2021-06-11 14:56:09</date>
              <date type="whenProduced">2021-08</date>
              <date type="whenEndEmbargoed">2021-10-20</date>
              <ref type="file" target="https://hal.science/hal-03223991v1/document">
                <date notBefore="2021-10-20"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://hal.science/hal-03223991v1/file/Tebani%20et%20al.%20-%202021%20-%20Large-Scale%20Screening%20of%20Lipase%20Acid%20Deficiency%20in.pdf" id="file-3258374-2861294">
                <date notBefore="2021-10-20"/>
              </ref>
              <ref type="annex" n="0" target="https://hal.science/hal-03223991v1/file/data.xlsx" id="file-3258374-2861295">
                <date notBefore="2021-06-11"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="113861">
                <persName>
                  <forename>Laurent</forename>
                  <surname>Jonchère</surname>
                </persName>
                <email type="md5">dc1f1e9bdb3dc2065f8bf1bfd5663118</email>
                <email type="domain">univ-rennes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-03223991</idno>
            <idno type="halUri">https://hal.science/hal-03223991</idno>
            <idno type="halBibtex">tebani:hal-03223991</idno>
            <idno type="halRefHtml">&lt;i&gt;Clinica Chimica Acta&lt;/i&gt;, 2021, 519 (.), pp.64-69. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.cca.2021.04.005"&gt;&amp;#x27E8;10.1016/j.cca.2021.04.005&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Clinica Chimica Acta, 2021, 519 (.), pp.64-69. &amp;#x27E8;10.1016/j.cca.2021.04.005&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-3258374-2861294"/><ref corresp="#file-3258374-2861295"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="UNICE">Université Nice Sophia Antipolis</idno>
            <idno type="stamp" n="UNIV-BOURGOGNE">Université Bourgogne Europe</idno>
            <idno type="stamp" n="UNIV-TLSE3">Université de Toulouse</idno>
            <idno type="stamp" n="UNIV-RENNES1">Université de Rennes 1</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-PICARDIE">Université de Picardie Jules Verne</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="U938" corresp="SORBONNE-UNIVERSITE">Centre de recherche Saint-Antoine - UMR S938</idno>
            <idno type="stamp" n="HL">Publications CHU Rennes</idno>
            <idno type="stamp" n="STATS-UR1">Statistiques-HAL-UR1</idno>
            <idno type="stamp" n="COMUE-NORMANDIE">Normandie Université</idno>
            <idno type="stamp" n="NUMECAN">Nutrition, Métabolismes et Cancer</idno>
            <idno type="stamp" n="NUMECAN-CIMIAD">Fermée CIMIAD</idno>
            <idno type="stamp" n="UR1-UFR-SVE">UFR SVE Sciences de la vie et de l'environnement</idno>
            <idno type="stamp" n="UR1-HAL">Publications labos UR1 dans HAL-Rennes 1</idno>
            <idno type="stamp" n="UR1-SDV">UR1 - publications SDV</idno>
            <idno type="stamp" n="LNC-UMR866" corresp="UNIV-BOURGOGNE">Lipides Nutrition Cancer - UMR866</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="BS">Biologie-Santé</idno>
            <idno type="stamp" n="UNIV-MONTPELLIER">Université de Montpellier</idno>
            <idno type="stamp" n="UNIV-COTEDAZUR">Université Côte d'Azur</idno>
            <idno type="stamp" n="TEST-UR-CSS">TEST Université de Rennes CSS</idno>
            <idno type="stamp" n="UNIV-RENNES">Université de Rennes</idno>
            <idno type="stamp" n="UNIROUEN">Université de Rouen Normandie</idno>
            <idno type="stamp" n="CHU-UNIV-PARIS5">Les centres hospitaliers de Paris Descartes</idno>
            <idno type="stamp" n="SORBONNE-UNIVERSITE">Sorbonne Université</idno>
            <idno type="stamp" n="SORBONNE-UNIV" corresp="SORBONNE-UNIVERSITE">Sorbonne Université 01/01/2018</idno>
            <idno type="stamp" n="SU-MEDECINE" corresp="SORBONNE-UNIVERSITE">Faculté de Santé de Sorbonne Université</idno>
            <idno type="stamp" n="CHU-CLERMONTFERRAND">CHU DE CLERMONT FERRAND</idno>
            <idno type="stamp" n="GPMCND">U1245 - Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques </idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UNIVERSITE-PARIS" corresp="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UP-SANTE">Université Paris Cité - Faculté de Santé</idno>
            <idno type="stamp" n="TEST-HALCNRS">Collection test HAL CNRS</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="NUMECAN-METHER" corresp="NUMECAN">NUMECAN équipe METHER - Métaux, Pathologies et Thérapies vectorisées</idno>
            <idno type="stamp" n="SU-TI">Sorbonne Université - Texte Intégral</idno>
            <idno type="stamp" n="UR1-BIO-SA">Pôle UnivRennes - Biologie-Santé</idno>
            <idno type="stamp" n="U-PICARDIE">Université de Picardie Jules Verne</idno>
            <idno type="stamp" n="GRAP" corresp="U-PICARDIE">Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247</idno>
            <idno type="stamp" n="ALLIANCE-SU"> Alliance Sorbonne Université</idno>
            <idno type="stamp" n="C3M">Collection du Centre Méditerranéen de Médecine Moléculaire</idno>
            <idno type="stamp" n="UNIV-UT3">Université Toulouse 3</idno>
            <idno type="stamp" n="UT3-INP">Université de Toulouse / Toulouse INP</idno>
            <idno type="stamp" n="UT3-TOULOUSEINP">Université de Toulouse / Toulouse INP</idno>
            <idno type="stamp" n="UM-2015-2021" corresp="UNIV-MONTPELLIER">Université de Montpellier (2015-2021)</idno>
            <idno type="stamp" n="TEST3-HALCNRS">TEST3-HALCNRS</idno>
            <idno type="stamp" n="CERPOP">CERPOP</idno>
            <idno type="stamp" n="INSTITUT-AGRO">Institut Agro</idno>
            <idno type="stamp" n="CERPOP-VIEILLISSEMENT" corresp="CERPOP">VIEILLISSEMENT</idno>
            <idno type="stamp" n="CTM_UMR1231" corresp="UNIV-BOURGOGNE">CTM</idno>
            <idno type="stamp" n="UNIV-COTEDAZUR_COLLECTION_DEFAUT">UNIV-COTEDAZUR_COLLECTION_DEFAUT</idno>
            <idno type="stamp" n="SUPRA_-SVE6">SVE6 - Maladies humaines</idno>
            <idno type="stamp" n="CBG">Cancer and Brain Genomics </idno>
            <idno type="stamp" n="IAB_GRENOBLE">IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble)</idno>
            <idno type="stamp" n="TEST-NICE">test nice</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Large-scale screening of lipase acid deficiency in at risk population</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Abdellah</forename>
                    <surname>Tebani</surname>
                  </persName>
                  <email type="md5">84b524be981fbddac4a3813d565bba0a</email>
                  <email type="domain">chu-rouen.fr</email>
                  <idno type="idhal" notation="numeric">809950</idno>
                  <idno type="halauthorid" notation="string">1152334-809950</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8901-2678</idno>
                  <idno type="IDREF">https://www.idref.fr/22363526X</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-6868-2018</idno>
                  <idno type="VIAF">https://viaf.org/viaf/193151836609520402600</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-6868-2018</idno>
                  <affiliation ref="#struct-519394"/>
                  <affiliation ref="#struct-300147"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bénédicte</forename>
                    <surname>Sudrié-Arnaud</surname>
                  </persName>
                  <idno type="halauthorid">1689688-0</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Hela</forename>
                    <surname>Boudabous</surname>
                  </persName>
                  <idno type="halauthorid">1422072-0</idno>
                  <affiliation ref="#struct-207896"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anais</forename>
                    <surname>Brassier</surname>
                  </persName>
                  <idno type="halauthorid">2156430-0</idno>
                  <affiliation ref="#struct-414766"/>
                  <affiliation ref="#struct-1004662"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Rodolphe</forename>
                    <surname>Anty</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">761750</idno>
                  <idno type="halauthorid" notation="string">417242-761750</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8194-9805</idno>
                  <affiliation ref="#struct-180122"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sarah</forename>
                    <surname>Snanoudj</surname>
                  </persName>
                  <idno type="halauthorid">1637898-0</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Armand</forename>
                    <surname>Abergel</surname>
                  </persName>
                  <email type="md5">0ff4d0c65bd4051ab42235966df2dfa7</email>
                  <email type="domain">chu-clermontferrand.fr</email>
                  <idno type="idhal" notation="numeric">763073</idno>
                  <idno type="halauthorid" notation="string">489930-763073</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7480-1052</idno>
                  <idno type="IDREF">https://www.idref.fr/109301269</idno>
                  <idno type="VIAF">https://viaf.org/viaf/208228281</idno>
                  <idno type="VIAF">https://viaf.org/viaf/306320681</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000139574915</idno>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie-Thérèse</forename>
                    <surname>Abi Warde</surname>
                  </persName>
                  <idno type="halauthorid">1621423-0</idno>
                  <affiliation ref="#struct-300149"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Edouard</forename>
                    <surname>Bardou-Jacquet</surname>
                  </persName>
                  <idno type="halauthorid">523715-0</idno>
                  <affiliation ref="#struct-480788"/>
                  <affiliation ref="#struct-301327"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Reda</forename>
                    <surname>Belbouab</surname>
                  </persName>
                  <idno type="halauthorid">1714355-0</idno>
                  <affiliation ref="#struct-1192911"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Eloi</forename>
                    <surname>Blanchet</surname>
                  </persName>
                  <idno type="halauthorid">2206356-0</idno>
                  <affiliation ref="#struct-1077089"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Corinne</forename>
                    <surname>Borderon</surname>
                  </persName>
                  <idno type="halauthorid">1234073-0</idno>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Pierre</forename>
                    <surname>Bronowicki</surname>
                  </persName>
                  <email type="md5">221f64c47bc185c3f9bf43d9ed0a506b</email>
                  <email type="domain">chu-nancy.fr</email>
                  <idno type="idhal" notation="numeric">1213521</idno>
                  <idno type="halauthorid" notation="string">355189-1213521</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-1631-500X</idno>
                  <idno type="IDREF">https://www.idref.fr/077913604</idno>
                  <affiliation ref="#struct-300157"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bertrand</forename>
                    <surname>Cariou</surname>
                  </persName>
                  <email type="md5">1eed1f2b671cbc31cf91c6a2af157d87</email>
                  <email type="domain">univ-nantes.fr</email>
                  <idno type="idhal" notation="numeric">761594</idno>
                  <idno type="halauthorid" notation="string">410249-761594</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1580-8040</idno>
                  <idno type="IDREF">https://www.idref.fr/075934981</idno>
                  <affiliation ref="#struct-474972"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Claire</forename>
                    <surname>Carette</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">776094</idno>
                  <idno type="halauthorid" notation="string">975256-776094</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8175-0369</idno>
                  <idno type="IDREF">https://www.idref.fr/087685159</idno>
                  <affiliation ref="#struct-300119"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Myriam</forename>
                    <surname>Dabbas</surname>
                  </persName>
                  <idno type="halauthorid">1876767-0</idno>
                  <affiliation ref="#struct-414766"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Hélène</forename>
                    <surname>Dranguet</surname>
                  </persName>
                  <idno type="halauthorid">1707536-0</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Victor</forename>
                    <surname>de Ledinghen</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">756883</idno>
                  <idno type="halauthorid" notation="string">159892-756883</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6414-1951</idno>
                  <affiliation ref="#struct-495627"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean</forename>
                    <surname>Ferrières</surname>
                  </persName>
                  <email type="md5">9a93364fb6dcec474b47819b98eb0b17</email>
                  <email type="domain">mail.cict.fr</email>
                  <idno type="idhal" notation="numeric">1064118</idno>
                  <idno type="halauthorid" notation="string">158571-1064118</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6144-1297</idno>
                  <idno type="IDREF">https://www.idref.fr/061532940</idno>
                  <affiliation ref="#struct-1160981"/>
                  <affiliation ref="#struct-101902"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Maeva</forename>
                    <surname>Guillaume</surname>
                  </persName>
                  <idno type="halauthorid">1237001-0</idno>
                  <affiliation ref="#struct-300075"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michel</forename>
                    <surname>Krempf</surname>
                  </persName>
                  <idno type="halauthorid">305750-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Florence</forename>
                    <surname>Lacaille</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">769724</idno>
                  <idno type="halauthorid" notation="string">745209-769724</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5272-4970</idno>
                  <affiliation ref="#struct-414766"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Dominique</forename>
                    <surname>Larrey</surname>
                  </persName>
                  <email type="md5">5aad1f0c817f20f72c0bb128156047f2</email>
                  <email type="domain">chu-montpellier.fr</email>
                  <idno type="idhal" notation="numeric">759679</idno>
                  <idno type="halauthorid" notation="string">308497-759679</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0892-3489</idno>
                  <affiliation ref="#struct-443668"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Vincent</forename>
                    <surname>Leroy</surname>
                  </persName>
                  <idno type="halauthorid">7566-0</idno>
                  <affiliation ref="#struct-1043222"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marietta</forename>
                    <surname>Musikas</surname>
                  </persName>
                  <idno type="halauthorid">2206357-0</idno>
                  <affiliation ref="#struct-300185"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Eric</forename>
                    <surname>Nguyen-Khac</surname>
                  </persName>
                  <email type="md5">96b5d383b0281131d1e737cbf077f291</email>
                  <email type="domain">chu-amiens.fr</email>
                  <idno type="idhal" notation="numeric">863504</idno>
                  <idno type="halauthorid" notation="string">417581-863504</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8672-4146</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/FMD-8891-2022</idno>
                  <idno type="IDREF">https://www.idref.fr/081127634</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/FMD-8891-2022</idno>
                  <affiliation ref="#struct-580112"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Denis</forename>
                    <surname>Ouzan</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">769426</idno>
                  <idno type="halauthorid" notation="string">737253-769426</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8035-2062</idno>
                  <affiliation ref="#struct-469997"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Marc</forename>
                    <surname>Perarnau</surname>
                  </persName>
                  <idno type="halauthorid">448119-0</idno>
                  <affiliation ref="#struct-179009"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Carine</forename>
                    <surname>Pilon</surname>
                  </persName>
                  <idno type="halauthorid">1685218-0</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Vlad</forename>
                    <surname>Ratzlu</surname>
                  </persName>
                  <idno type="halauthorid">2206358-0</idno>
                  <affiliation ref="#struct-541912"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alice</forename>
                    <surname>Thebaut</surname>
                  </persName>
                  <idno type="halauthorid">2206359-0</idno>
                  <affiliation ref="#struct-312432"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Thierry</forename>
                    <surname>Thevenot</surname>
                  </persName>
                  <idno type="halauthorid">448181-0</idno>
                  <affiliation ref="#struct-300165"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Isabelle</forename>
                    <surname>Tragin</surname>
                  </persName>
                  <idno type="halauthorid">2206360-0</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Valérie</forename>
                    <surname>Triolo</surname>
                  </persName>
                  <idno type="halauthorid">2206361-0</idno>
                  <affiliation ref="#struct-107940"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bruno</forename>
                    <surname>Verges</surname>
                  </persName>
                  <email type="md5">6e1db1a76ce1ba3e1d0fccd4423e6499</email>
                  <email type="domain">chu-dijon.fr</email>
                  <idno type="idhal" notation="string">bruno-verges</idno>
                  <idno type="idhal" notation="numeric">13656</idno>
                  <idno type="halauthorid" notation="string">4815-13656</idno>
                  <idno type="IDREF">https://www.idref.fr/030858453</idno>
                  <affiliation ref="#struct-489317"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sabrina</forename>
                    <surname>Vergnaud</surname>
                  </persName>
                  <idno type="halauthorid">508499-0</idno>
                  <affiliation ref="#struct-257328"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">Soumeya</forename>
                    <surname>Bekri</surname>
                  </persName>
                  <email type="md5">5e5f3467a3d4af860fffddb6f4dd0ba3</email>
                  <email type="domain">univ-rouen.fr</email>
                  <idno type="idhal" notation="numeric">767750</idno>
                  <idno type="halauthorid" notation="string">661326-767750</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6184-7270</idno>
                  <idno type="IDREF">https://www.idref.fr/128937300</idno>
                  <affiliation ref="#struct-519394"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">11739</idno>
                <idno type="issn">0009-8981</idno>
                <title level="j">Clinica Chimica Acta</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">519</biblScope>
                  <biblScope unit="issue">.</biblScope>
                  <biblScope unit="pp">64-69</biblScope>
                  <date type="datePub">2021-08</date>
                  <date type="dateEpub">2021-04-15</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.cca.2021.04.005</idno>
              <idno type="pubmed">33857477</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">DBS</term>
                <term xml:lang="en">Acid lipase deficiency</term>
                <term xml:lang="en">CESD</term>
                <term xml:lang="en">Cholesterol ester storage disease</term>
                <term xml:lang="en">Wolman</term>
                <term xml:lang="en">Screening</term>
                <term xml:lang="en">LAL</term>
                <term xml:lang="en">Dried blood spot</term>
              </keywords>
              <classCode scheme="mesh">Cholesterol Ester Storage Disease* / diagnosis</classCode>
              <classCode scheme="mesh">Cholesterol Ester Storage Disease* / genetics</classCode>
              <classCode scheme="mesh">Wolman Disease* / diagnosis</classCode>
              <classCode scheme="mesh">Wolman Disease* / genetics</classCode>
              <classCode scheme="mesh">Cholesterol Esters</classCode>
              <classCode scheme="mesh">Female</classCode>
              <classCode scheme="mesh">Humans</classCode>
              <classCode scheme="mesh">Infant, Newborn</classCode>
              <classCode scheme="mesh">Lipase</classCode>
              <classCode scheme="mesh">Pregnancy</classCode>
              <classCode scheme="mesh">Sterol Esterase / genetics</classCode>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>BACKGROUND: Lysosomal acid lipase deficiency (LALD, OMIM#278000) is a rare lysosomal disorder with an autosomal recessive inheritance. The main clinical manifestations are related to a progressive accumulation of cholesteryl esters, triglycerides or both within the lysosome in different organs such as the liver, spleen, and cardiovascular system. A wide range of clinical severity is associated with LALD including a severe very rare antenatal/neonatal/infantile phenotype named Wolman disease and a late-onset form named cholesteryl ester storage disease (CESD). METHODS: This study aimed to investigate a cohort of at-risk patients (4174) presenting with clinical or biological signs consistent with LALD using the assessment of LAL activity on dried blood spots. RESULTS: LAL activity was lower than 0.05 nmol/punch/L (cut-off: 0.12) in 19 patients including 13 CESD and 6 Wolman. Molecular study has been conducted in 17 patients and succeeded in identifying 34 mutated alleles. Fourteen unique variants have been characterized, 7 of which are novel.CONCLUSION: This study allowed to identify a series of patients and expanded the molecular spectrum knowledge of LALD. Besides, a new screening criteria grid based on the clinical/biological data from our study and the literature has been proposed in order to enhance the diagnosis rate in at risk populations.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-519394" status="OLD">
          <idno type="IdRef">198011067</idno>
          <idno type="RNSR">201722543J</idno>
          <orgName>Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques</orgName>
          <orgName type="acronym">GPMCND</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>22, Boulevard Gambetta 76183 Rouen Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://medecine-pharmacie.univ-rouen.fr/genomic-and-personalized-medicine-in-cancer-and-neurological-disorders-279535.kjsp</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300318" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
            <relation name="U1245" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300147" status="VALID">
          <idno type="IdRef">169975681</idno>
          <idno type="ROR">https://ror.org/00cxy0s05</idno>
          <orgName>CHU Rouen</orgName>
          <desc>
            <address>
              <addrLine>1 rue de Germont 76031 Rouen cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-rouen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-207896" status="VALID">
          <idno type="IdRef">112859585</idno>
          <idno type="ISNI">0000000122959819</idno>
          <idno type="ROR">https://ror.org/029cgt552</idno>
          <idno type="Wikidata">Q3551684</idno>
          <orgName>Tunis El Manar University [University of Tunis El Manar] [Tunisia] = Université de Tunis El Manar [Tunisie] = جامعة تونس المنار (ar)</orgName>
          <orgName type="acronym">UTM</orgName>
          <date type="start">1987-01-01</date>
          <desc>
            <address>
              <addrLine>Campus Universitaire Farhat Hached B.P. n° 94 - ROMMANA 1068 Tunis</addrLine>
              <country key="TN"/>
            </address>
            <ref type="url">http://www.utm.rnu.tn/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-414766" status="VALID">
          <orgName>Hôpital Necker - Enfants Malades [AP-HP]</orgName>
          <desc>
            <address>
              <addrLine>149 Rue de Sèvres 75015 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://hopital-necker.aphp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1004662" status="VALID">
          <idno type="IdRef">188538119</idno>
          <idno type="ISNI">0000 0004 0620 6624</idno>
          <idno type="RNSR">201420829J</idno>
          <idno type="ROR">https://ror.org/04z4fen17</idno>
          <orgName>Imagine - Institut des maladies génétiques (IHU)</orgName>
          <orgName type="acronym">Imagine - U1163</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>IHU Imagine, 156 rue de Vaugirard, 75015 PARIS et 24 Boulevard du Montparnasse, 75015 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.institutimagine.org/fr/</ref>
          </desc>
          <listRelation>
            <relation name="U1163" active="#struct-303623" type="direct"/>
            <relation name="UMR_S 1163" active="#struct-557826" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-180122" status="VALID">
          <orgName>Centre méditerranéen de médecine moléculaire</orgName>
          <orgName type="acronym">C3M</orgName>
          <desc>
            <address>
              <addrLine>Hôpital de l'Archet, 151 rte Saint Antoine de Ginestiere 06204 Nice Cedex 3</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-117617" type="direct"/>
            <relation name="U1065" active="#struct-303623" type="direct"/>
            <relation name="UMR_S1065" active="#struct-1039632" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300144" status="VALID">
          <idno type="IdRef">026606836</idno>
          <idno type="ISNI">0000000406394151</idno>
          <idno type="ROR">https://ror.org/02tcf7a68</idno>
          <orgName>CHU Clermont-Ferrand</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300149" status="VALID">
          <orgName>Centre Hospitalier Universitaire [Strasbourg]</orgName>
          <orgName type="acronym">CHU Strasbourg</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chru-strasbourg.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-211628" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-480788" status="VALID">
          <idno type="IdRef">28086812X</idno>
          <idno type="RNSR">201722267J</idno>
          <idno type="ROR">https://ror.org/03zb6nw87</idno>
          <orgName>Nutrition, Métabolismes et Cancer</orgName>
          <orgName type="acronym">NuMeCan</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Campus Villejean (Bât 8) - CHU Rennes (Bât 15) - Université de Rennes 1, 2 Avenue du Professeur Léon Bernard, 35043 Rennes, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://numecan.univ-rennes.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-105160" type="direct"/>
            <relation name="U1317 / UMR1317" active="#struct-303623" type="direct"/>
            <relation name="UMR 1341" active="#struct-577435" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301327" status="VALID">
          <idno type="ROR">https://ror.org/05qec5a53</idno>
          <orgName>Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]</orgName>
          <desc>
            <address>
              <addrLine>2 Rue Henri le Guilloux, 35000 Rennes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1192911" status="VALID">
          <orgName>Université de Batna 2 - Mostefa Ben Boulaid</orgName>
          <orgName type="acronym">Batna 2</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Université Batna 2, 53, Route de Constantine Fesdis, Batna 05078, Algérie</addrLine>
              <country key="DZ"/>
            </address>
            <ref type="url">https://univ-batna2.dz/language/fr/home-rtl-francais/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1077089" status="VALID">
          <orgName>Hôpitaux La Rochelle Ré Aunis [Groupe hospitalier littoral Atlantique]</orgName>
          <desc>
            <address>
              <addrLine>Hôpital de la La Rochelle,  rue du Dr Albert Schweitzer, 17000 La Rochelle</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ch-larochelle.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300157" status="VALID">
          <orgName>Centre Hospitalier Régional Universitaire de Nancy</orgName>
          <orgName type="acronym">CHRU Nancy</orgName>
          <desc>
            <address>
              <addrLine>Siège social : 29 avenue du Maréchal de Lattre de Tassigny, CO 60034, 54035 NANCY CEDEXHôpital Central : 29 Avenue du Maréchal de Lattre de Tassigny, 54035 NancyHôpitaux de Brabois / Enfants : Rue du Morvan, 54500 Vandœuvre-lès-NancyMaternité régionale :10 Avenue Dr Heydenreich, 54000 Nancy</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-nancy.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-474972" status="VALID">
          <idno type="IdRef">034926445</idno>
          <idno type="ROR">https://ror.org/05c1qsg97</idno>
          <idno type="Wikidata">Q2945767</idno>
          <orgName>Centre Hospitalier Universitaire de Nantes = Nantes University Hospital</orgName>
          <orgName type="acronym">CHU Nantes</orgName>
          <desc>
            <address>
              <addrLine>1 Place Alexis-Ricordeau, 44000 Nantes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-nantes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300119" status="VALID">
          <idno type="IdRef">052497380</idno>
          <idno type="ROR">https://ror.org/016vx5156</idno>
          <orgName>Hôpital Européen Georges Pompidou [APHP]</orgName>
          <orgName type="acronym">HEGP</orgName>
          <desc>
            <address>
              <addrLine>20, rue Leblanc, 75015 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://hopital-georgespompidou.aphp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-353414" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-495627" status="VALID">
          <orgName>CHU Pessac</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="researchteam" xml:id="struct-1160981" status="OLD">
          <orgName>Equipe AGING (CERPOP)</orgName>
          <date type="start">2021-01-01</date>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>37 allées J. Guesde 31000 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://cerpop.inserm.fr/equipe-emergente</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1061597" type="direct"/>
            <relation active="#struct-217752" type="indirect"/>
            <relation active="#struct-443875" type="indirect"/>
            <relation name="UMR1295" active="#struct-303623" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-101902" status="VALID">
          <orgName>Service Cardiologie [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Cardiologie A et B. Pôle Cardiovasculaire et Métabolique, 1, avenue du Professeur Jean Poulhès - TSA 50032 - 31059 Toulouse cedex 9</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-1152891" type="direct"/>
            <relation active="#struct-300075" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300075" status="VALID">
          <orgName>Centre Hospitalier Universitaire de Toulouse</orgName>
          <orgName type="acronym">CHU Toulouse</orgName>
          <desc>
            <address>
              <addrLine>regroupe les hôpitaux  Purpan, Rangueil, Pierre-Paul Riquet, Larey, Paule de Viguier, Hôtel Dieu Saint-Jacques, La Grave, etc.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-toulouse.fr</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-443668" status="OLD">
          <idno type="RNSR">200716494C</idno>
          <idno type="ROR">https://ror.org/00b8mh310</idno>
          <orgName>Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB)</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>Institute for Regenerative Medicine and Biotherapy  - 80 rue Augustin Fliche 34295 Montpellier - Cedex 5</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-258773" type="direct"/>
            <relation name="U1183" active="#struct-303623" type="direct"/>
            <relation active="#struct-410122" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1043222" status="VALID">
          <idno type="IdRef">200912658</idno>
          <idno type="RNSR">201622378J</idno>
          <idno type="ROR">https://ror.org/05kwbf598</idno>
          <orgName>Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble)</orgName>
          <orgName type="acronym">IAB</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Institut pour l'Avancée des BiosciencesCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309Site Santé - Allée des Alpes 38700 La Tronche</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://iab-grenoble.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-200221" type="direct"/>
            <relation active="#struct-199980" type="indirect"/>
            <relation active="#struct-257328" type="direct"/>
            <relation name="U1209" active="#struct-303623" type="direct"/>
            <relation name="UMR5309" active="#struct-441569" type="direct"/>
            <relation active="#struct-1042703" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300185" status="VALID">
          <idno type="IdRef">031245382</idno>
          <idno type="ISNI">0000000404720160</idno>
          <idno type="ROR">https://ror.org/027arzy69</idno>
          <idno type="Wikidata">Q2945740</idno>
          <orgName>CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie</orgName>
          <orgName type="acronym">CHU Caen Normandie</orgName>
          <desc>
            <address>
              <addrLine>Avenue de la Côte de Nacre 14000 Caen</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-caen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-580112" status="VALID">
          <idno type="IdRef">195706684</idno>
          <idno type="RNSR">200720140R</idno>
          <idno type="ROR">https://ror.org/01c62av11</idno>
          <orgName>Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 UPJV</orgName>
          <orgName type="acronym">GRAP</orgName>
          <date type="start">2007-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Picardie Jules Verne - CURS - CHU Sud - avenue Laënnec - 80054 AMIENS CEDEX 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://grap.u-picardie.fr</ref>
          </desc>
          <listRelation>
            <relation name="ERI24" active="#struct-300258" type="direct"/>
            <relation name="U1247" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-469997" status="VALID">
          <idno type="ROR">https://ror.org/005t0ps98</idno>
          <orgName>Institut Arnault Tzanck</orgName>
          <desc>
            <address>
              <addrLine>Institut Arnaud Tzanck, Liver Unit, St. Laurent du Var, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://saintlaurentduvar.tzanck.org/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-179009" status="VALID">
          <idno type="ROR">https://ror.org/00jpq0w62</idno>
          <orgName>Centre Hospitalier Régional Universitaire de Tours</orgName>
          <orgName type="acronym">CHRU Tours</orgName>
          <desc>
            <address>
              <addrLine>Centre Hospitalier Régional Universitaire de Tours2 Boulevard Tonnellé 37044 Tours cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-tours.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-541912" status="VALID">
          <idno type="RNSR">200918542V</idno>
          <orgName>Centre de Recherche Saint-Antoine</orgName>
          <orgName type="acronym">CRSA</orgName>
          <desc>
            <address>
              <addrLine>Bâtiment Kourilsky34 rue Crozatier75012 PARISSorbonne Université27 rue Chaligny75012 PARIS</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.crsa.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation name="U938" active="#struct-303623" type="direct"/>
            <relation name="UMRS_938" active="#struct-413221" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-312432" status="VALID">
          <orgName>Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]</orgName>
          <desc>
            <address>
              <addrLine>78 Rue du Général Leclerc 94270 Le Kremlin-Bicêtre</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://hopital-bicetre.aphp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300165" status="VALID">
          <orgName>Centre Hospitalier Régional Universitaire de Besançon</orgName>
          <orgName type="acronym">CHRU Besançon</orgName>
          <desc>
            <address>
              <addrLine>3, boulevard A. Fleming - 25030 Besançon Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-besancon.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-107940" status="VALID">
          <orgName>CHU Nice [Cimiez]</orgName>
          <desc>
            <address>
              <addrLine>4 avenue Reine Victoria 06003 Nice Cedex 1</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-443277" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-489317" status="OLD">
          <idno type="IdRef">15975979X</idno>
          <idno type="RNSR">200716508T</idno>
          <idno type="ROR">https://ror.org/04d70nb60</idno>
          <orgName>Lipides - Nutrition - Cancer [Dijon - U1231]</orgName>
          <orgName type="acronym">LNC</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>Université de Bourgogne - Faculte de medecine - 7, boulevard Jeanne d'Arc - BP 87900 - 21079 Dijon Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://inserm-u866.u-bourgogne.fr/index.php</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300270" type="direct"/>
            <relation name="U1231" active="#struct-303623" type="direct"/>
            <relation name="UMR_S 866" active="#struct-415469" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-257328" status="VALID">
          <idno type="IdRef">034137076</idno>
          <idno type="ROR">https://ror.org/041rhpw39</idno>
          <orgName>CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble</orgName>
          <orgName type="acronym">CHUGA</orgName>
          <desc>
            <address>
              <addrLine>CS 1021738043 Grenoble cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300318" status="VALID">
          <idno type="IdRef">026403919</idno>
          <idno type="ISNI">0000000121083034</idno>
          <idno type="ROR">https://ror.org/03nhjew95</idno>
          <orgName>Université de Rouen Normandie</orgName>
          <orgName type="acronym">UNIROUEN</orgName>
          <date type="start">1966-01-01</date>
          <desc>
            <address>
              <addrLine>1, rue Thomas Becket 76821 Mont-Saint-Aignan Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-rouen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-455934" status="VALID">
          <idno type="IdRef">190906332</idno>
          <idno type="ISNI">0000000417859671 </idno>
          <idno type="ROR">https://ror.org/01k40cz91</idno>
          <orgName>Normandie Université</orgName>
          <orgName type="acronym">NU</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.normandie-univ.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300068" status="VALID">
          <idno type="ROR">https://ror.org/00pg5jh14</idno>
          <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
          <orgName type="acronym">AP-HP</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-557826" status="VALID">
          <idno type="IdRef">236453505</idno>
          <idno type="ISNI">0000 0004 7885 7602</idno>
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris Cité</orgName>
          <orgName type="acronym">UPCité</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>85 boulevard Saint-Germain75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://u-paris.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-117617" status="VALID">
          <idno type="IdRef">026403498</idno>
          <idno type="ISNI">0000000123372892</idno>
          <idno type="ROR">https://ror.org/02k9vew78</idno>
          <orgName>Université Nice Sophia Antipolis (1965 - 2019)</orgName>
          <orgName type="acronym">UNS</orgName>
          <date type="start">1965-10-23</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Parc Valrose, 06100 Nice</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://unice.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1039632" status="VALID">
          <idno type="IdRef">241035694</idno>
          <idno type="ROR">https://ror.org/019tgvf94</idno>
          <orgName>Université Côte d'Azur</orgName>
          <orgName type="acronym">UniCA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Parc Valrose, 28, avenue Valrose 06108 Nice Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://univ-cotedazur.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-211628" status="VALID">
          <idno type="IdRef">030378842</idno>
          <idno type="ROR">https://ror.org/04bckew43</idno>
          <orgName>Hôpitaux Universitaires de Strasbourg</orgName>
          <orgName type="acronym">HUS</orgName>
          <desc>
            <address>
              <addrLine>1 place de l'hôpital BP 426 67091 Strasbourg cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chru-strasbourg.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-105160" status="VALID">
          <idno type="IdRef">26693823X</idno>
          <idno type="ROR">https://ror.org/015m7wh34</idno>
          <orgName>Université de Rennes</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>
            <address>
              <addrLine>Campus de Beaulieu, 263 avenue Général Leclerc, CS 74205, 35042 RENNES CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-577435" status="VALID">
          <idno type="ROR">https://ror.org/003vg9w96</idno>
          <orgName>Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement</orgName>
          <orgName type="acronym">INRAE</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-353414" status="VALID">
          <orgName>Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest</orgName>
          <orgName type="acronym">HUPO</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://hopitaux-parisouest.aphp.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-1061597" status="OLD">
          <idno type="IdRef">252835271</idno>
          <orgName>Centre d'Epidémiologie et de Recherche en santé des POPulations</orgName>
          <orgName type="acronym">CERPOP</orgName>
          <date type="start">2021-01-01</date>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>37 allées J. Guesde 31000 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.u1027.inserm.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-217752" type="direct"/>
            <relation active="#struct-443875" type="indirect"/>
            <relation name="UMR1295" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-217752" status="OLD">
          <idno type="IdRef">026404672</idno>
          <idno type="ISNI">0000000121617331</idno>
          <idno type="ROR">https://ror.org/02v6kpv12</idno>
          <idno type="Wikidata">Q1273188</idno>
          <orgName>Université Toulouse III - Paul Sabatier</orgName>
          <orgName type="acronym">UT3</orgName>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>118 route de Narbonne - 31062 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-tlse3.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-443875" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-443875" status="VALID">
          <idno type="ROR">https://ror.org/017tgbk05</idno>
          <orgName>Communauté d'universités et établissements de Toulouse</orgName>
          <orgName type="acronym">Comue de Toulouse</orgName>
          <desc>
            <address>
              <addrLine>41 Allée Jules Guesde, 31000 Toulouse</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-toulouse.fr/</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1152891" status="VALID">
          <orgName>Pôle Cardiovasculaire et Métabolique [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Toulouse</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300075" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-258773" status="VALID">
          <idno type="ISNI">000000009961060X</idno>
          <idno type="ROR">https://ror.org/04m6sq715</idno>
          <orgName>Centre Hospitalier Régional Universitaire [Montpellier]</orgName>
          <orgName type="acronym">CHRU Montpellier</orgName>
          <desc>
            <address>
              <addrLine>191 avenue du doyen Gaston Giraud 34295 Montpellier</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-montpellier.fr/fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-410122" status="OLD">
          <idno type="ISNI">0000000120970141</idno>
          <idno type="ROR">https://ror.org/051escj72</idno>
          <orgName>Université de Montpellier</orgName>
          <orgName type="acronym">UM</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>163 rue Auguste Broussonnet - 34090 Montpellier</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.umontpellier.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-200221" status="VALID">
          <orgName>Établissement Français du Sang Auvergne-Rhône-Alpes [Lyon]</orgName>
          <orgName type="acronym">EFS Auvergne-Rhône-Alpes - Lyon</orgName>
          <desc>
            <address>
              <addrLine>Site de Lyon. 3 Rue du Vercors 69364 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.efs.sante.fr/lefs-en-auvergne-rhone-alpes</ref>
          </desc>
          <listRelation>
            <relation active="#struct-199980" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-199980" status="VALID">
          <orgName>Établissement Français du Sang [La Plaine Saint-Denis]</orgName>
          <orgName type="acronym">EFS</orgName>
          <date type="start">2000-01-01</date>
          <desc>
            <address>
              <addrLine>20 Avenue du Stade de France 93218 La Plaine Saint Denis</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.dondusang.net</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300258" status="VALID">
          <idno type="IdRef">026403714</idno>
          <idno type="ISNI">0000 0001 0789 1385</idno>
          <idno type="ROR">https://ror.org/01gyxrk03</idno>
          <orgName>Université de Picardie Jules Verne</orgName>
          <orgName type="acronym">UPJV</orgName>
          <desc>
            <address>
              <addrLine>Chemin du Thil - 80000 Amiens</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.u-picardie.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-413221" status="VALID">
          <idno type="IdRef">221333754</idno>
          <idno type="ROR">https://ror.org/02en5vm52</idno>
          <orgName>Sorbonne Université</orgName>
          <orgName type="acronym">SU</orgName>
          <date type="start">2018-01-01</date>
          <desc>
            <address>
              <addrLine>21 rue de l’École de médecine - 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-universite.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-443277" status="VALID">
          <orgName>Hôpital Cimiez [Nice]</orgName>
          <orgName type="acronym">CHU</orgName>
          <desc>
            <address>
              <addrLine>4, Avenue Reine Victoria - CS 91179 - 06003 Nice Cedex 1</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300270" status="OLD">
          <idno type="IdRef">02819005X</idno>
          <idno type="ISNI">0000000122989313</idno>
          <idno type="ROR">https://ror.org/03k1bsr36</idno>
          <orgName>Université de Bourgogne</orgName>
          <orgName type="acronym">UB</orgName>
          <date type="end">2024-12-31</date>
          <desc>
            <address>
              <addrLine>Maison de l'université - Esplanade Érasme - BP 27877 - 21078 Dijon cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-bourgogne.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-415469" status="OLD">
          <idno type="IdRef">13996634X</idno>
          <idno type="ROR">https://ror.org/03zek0r74</idno>
          <orgName>AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement</orgName>
          <date type="start">2009-03-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>26 Boulevard du Dr Petitjean - BP 87999 - 21079 Dijon cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.agrosupdijon.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>